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Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses.
Metwally H, Elbrashy MM, Ozawa T, Okuyama K, White JT, Tulyeu J, Søndergaard JN, Wing JB, Muratsu A, Matsumoto H, Ikawa M, Kishi H, Taniuchi I, Kishimoto T. Metwally H, et al. Among authors: kishi h. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2402226121. doi: 10.1073/pnas.2402226121. Epub 2024 Apr 15. Proc Natl Acad Sci U S A. 2024. PMID: 38621137
Gastrointestinal symptoms in COVID-19 and disease severity: a Japanese registry-based retrospective cohort study.
Matsubara Y, Kiyohara H, Mikami Y, Nanki K, Namkoong H, Chubachi S, Tanaka H, Azekawa S, Sugimoto S, Yoshimatsu Y, Sujino T, Takabayashi K, Hosoe N, Sato T, Ishii M, Hasegawa N, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Fukunaga K, Kanai T; Japan COVID-19 Task Force. Matsubara Y, et al. J Gastroenterol. 2024 Mar;59(3):195-208. doi: 10.1007/s00535-023-02071-x. Epub 2024 Jan 25. J Gastroenterol. 2024. PMID: 38270615
Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1.
Ozawa T, Ikeda Y, Chen L, Suzuki R, Hoshino A, Noguchi A, Kita S, Anraku Y, Igarashi E, Saga Y, Inasaki N, Taminishi S, Sasaki J, Kirita Y, Fukuhara H, Maenaka K, Hashiguchi T, Fukuhara T, Hirabayashi K, Tani H, Kishi H, Niimi H. Ozawa T, et al. Among authors: kishi h. Structure. 2024 Mar 7;32(3):263-272.e7. doi: 10.1016/j.str.2023.12.013. Epub 2024 Jan 15. Structure. 2024. PMID: 38228146
Secretory GFP reconstitution labeling of neighboring cells interrogates cell-cell interactions in metastatic niches.
Minegishi M, Kuchimaru T, Nishikawa K, Isagawa T, Iwano S, Iida K, Hara H, Miura S, Sato M, Watanabe S, Shiomi A, Mabuchi Y, Hamana H, Kishi H, Sato T, Sawaki D, Sato S, Hanazono Y, Suzuki A, Kohro T, Kadonosono T, Shimogori T, Miyawaki A, Takeda N, Shintaku H, Kizaka-Kondoh S, Nishimura S. Minegishi M, et al. Among authors: kishi h. Nat Commun. 2023 Dec 5;14(1):8031. doi: 10.1038/s41467-023-43855-2. Nat Commun. 2023. PMID: 38052804 Free PMC article.
Inhibition of IL-33 signaling ameliorate hepatic fibrosis with decreasing MCP-1 in a mouse model of diabetes and non-alcoholic steatohepatitis; comparison for luseogliflozin, an SGLT2 inhibitor.
Wakamatsu S, Jojima T, Hashiguchi M, Kishi H, Niitani T, Sakurai S, Iijima T, Kogai T, Tomaru T, Usui I, Aso Y. Wakamatsu S, et al. Among authors: kishi h. J Diabetes Complications. 2024 Jan;38(1):108650. doi: 10.1016/j.jdiacomp.2023.108650. Epub 2023 Nov 23. J Diabetes Complications. 2024. PMID: 38035640
590 results