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ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection.
Bredow C, Thery F, Wirth EK, Ochs S, Kespohl M, Kleinau G, Kelm N, Gimber N, Schmoranzer J, Voss M, Klingel K, Spranger J, Renko K, Ralser M, Mülleder M, Heuser A, Knobeloch KP, Scheerer P, Kirwan J, Brüning U, Berndt N, Impens F, Beling A. Bredow C, et al. Among authors: kirwan j. Cardiovasc Res. 2024 May 7;120(6):644-657. doi: 10.1093/cvr/cvae026. Cardiovasc Res. 2024. PMID: 38309955 Free PMC article.
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner PJ, Anandakumar H, Röwekamp I, Fiocca Vernengo F, Millet Pascual-Leone B, Krzanowski M, Sellmaier J, Brüning U, Fritsche-Guenther R, Pfannkuch L, Kurth F, Milek M, Igbokwe V, Löber U, Gutbier B, Holstein M, Heinz GA, Mashreghi MF, Schulte LN, Klatt AB, Caesar S, Wienhold SM, Offermanns S, Mack M, Witzenrath M, Jordan S, Beule D, Kirwan JA, Forslund SK, Wilck N, Bartolomaeus H, Heimesaat MM, Opitz B. Dörner PJ, et al. Among authors: kirwan ja. Nat Commun. 2024 Mar 30;15(1):2788. doi: 10.1038/s41467-024-47149-z. Nat Commun. 2024. PMID: 38555356 Free PMC article.
Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla T, Gollasch B, Kuich PHJL, Klug L, Rahn G, Busjahn A, Spuler S, Boschmann M, Kirwan JA, Luft FC, Kempa S. Opialla T, et al. Among authors: kirwan ja. Front Mol Biosci. 2022 Dec 21;9:1042231. doi: 10.3389/fmolb.2022.1042231. eCollection 2022. Front Mol Biosci. 2022. PMID: 36619172 Free PMC article.
Exploratory physiological experiments are not clinical trials.
Richter EA, James DE, Kirwan JP, Zierath JR. Richter EA, et al. Among authors: kirwan jp. Cell Metab. 2024 Apr 16:S1550-4131(24)00125-6. doi: 10.1016/j.cmet.2024.04.005. Online ahead of print. Cell Metab. 2024. PMID: 38670105 No abstract available.
Author Correction: Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP).
Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, Ginty F, Gonçalves JP, Hagood JS, Hickey JW, Kelleher NL, Laurent LC, Lin S, Lin Y, Liu H, Naba A, Nakayasu ES, Qian WJ, Radtke A, Robson P, Stockwell BR, Van de Plas R, Vlachos IS, Zhou M; HuBMAP Consortium; Börner K, Snyder MP. Jain S, et al. Nat Cell Biol. 2024 Mar 1. doi: 10.1038/s41556-024-01384-0. Online ahead of print. Nat Cell Biol. 2024. PMID: 38429479 No abstract available.
874 results