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Page 1
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Eccles SA, Aboagye EO, Ali S, Anderson AS, Armes J, Berditchevski F, Blaydes JP, Brennan K, Brown NJ, Bryant HE, Bundred NJ, Burchell JM, Campbell AM, Carroll JS, Clarke RB, Coles CE, Cook GJ, Cox A, Curtin NJ, Dekker LV, Silva Idos S, Duffy SW, Easton DF, Eccles DM, Edwards DR, Edwards J, Evans D, Fenlon DF, Flanagan JM, Foster C, Gallagher WM, Garcia-Closas M, Gee JM, Gescher AJ, Goh V, Groves AM, Harvey AJ, Harvie M, Hennessy BT, Hiscox S, Holen I, Howell SJ, Howell A, Hubbard G, Hulbert-Williams N, Hunter MS, Jasani B, Jones LJ, Key TJ, Kirwan CC, Kong A, Kunkler IH, Langdon SP, Leach MO, Mann DJ, Marshall JF, Martin L, Martin SG, Macdougall JE, Miles DW, Miller WR, Morris JR, Moss SM, Mullan P, Natrajan R, O'Connor JP, O'Connor R, Palmieri C, Pharoah PD, Rakha EA, Reed E, Robinson SP, Sahai E, Saxton JM, Schmid P, Smalley MJ, Speirs V, Stein R, Stingl J, Streuli CH, Tutt AN, Velikova G, Walker RA, Watson CJ, Williams KJ, Young LS, Thompson AM. Eccles SA, et al. Among authors: kirwan cc. Breast Cancer Res. 2013 Oct 1;15(5):R92. doi: 10.1186/bcr3493. Breast Cancer Res. 2013. PMID: 24286369 Free PMC article. Review.
Opportunities and priorities for breast surgical research.
Cutress RI, McIntosh SA, Potter S, Goyal A, Kirwan CC, Harvey J, Francis A, Carmichael AR, Vidya R, Vaidya JS, Fairbrother P, Benson JR, Reed MWR; Association of Breast Surgery Surgical Gap Analysis Working Group. Cutress RI, et al. Among authors: kirwan cc. Lancet Oncol. 2018 Oct;19(10):e521-e533. doi: 10.1016/S1470-2045(18)30511-4. Epub 2018 Oct 1. Lancet Oncol. 2018. PMID: 30303126 Review.
Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial.
Murray Brunt A, Haviland JS, Wheatley DA, Sydenham MA, Alhasso A, Bloomfield DJ, Chan C, Churn M, Cleator S, Coles CE, Goodman A, Harnett A, Hopwood P, Kirby AM, Kirwan CC, Morris C, Nabi Z, Sawyer E, Somaiah N, Stones L, Syndikus I, Bliss JM, Yarnold JR; FAST-Forward Trial Management Group. Murray Brunt A, et al. Among authors: kirwan cc. Lancet. 2020 May 23;395(10237):1613-1626. doi: 10.1016/S0140-6736(20)30932-6. Epub 2020 Apr 28. Lancet. 2020. PMID: 32580883 Free PMC article. Clinical Trial.
Increased peri-ductal collagen micro-organization may contribute to raised mammographic density.
McConnell JC, O'Connell OV, Brennan K, Weiping L, Howe M, Joseph L, Knight D, O'Cualain R, Lim Y, Leek A, Waddington R, Rogan J, Astley SM, Gandhi A, Kirwan CC, Sherratt MJ, Streuli CH. McConnell JC, et al. Among authors: kirwan cc. Breast Cancer Res. 2016 Jan 8;18(1):5. doi: 10.1186/s13058-015-0664-2. Breast Cancer Res. 2016. PMID: 26747277 Free PMC article.
Tissue Factor promotes breast cancer stem cell activity in vitro.
Shaker H, Harrison H, Clarke R, Landberg G, Bundred NJ, Versteeg HH, Kirwan CC. Shaker H, et al. Among authors: kirwan cc. Oncotarget. 2017 Apr 18;8(16):25915-25927. doi: 10.18632/oncotarget.13928. Oncotarget. 2017. PMID: 28033108 Free PMC article.
Patient-Reported Outcomes Over 5 Years After Whole- or Partial-Breast Radiotherapy: Longitudinal Analysis of the IMPORT LOW (CRUK/06/003) Phase III Randomized Controlled Trial.
Bhattacharya IS, Haviland JS, Kirby AM, Kirwan CC, Hopwood P, Yarnold JR, Bliss JM, Coles CE; IMPORT Trialists. Bhattacharya IS, et al. Among authors: kirwan cc. J Clin Oncol. 2019 Feb 1;37(4):305-317. doi: 10.1200/JCO.18.00982. Epub 2018 Dec 11. J Clin Oncol. 2019. PMID: 30532984 Free PMC article. Clinical Trial.
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