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Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA.
Krüger A, Oldenburg M, Chebrolu C, Beisser D, Kolter J, Sigmund AM, Steinmann J, Schäfer S, Hochrein H, Rahmann S, Wagner H, Henneke P, Hornung V, Buer J, Kirschning CJ. Krüger A, et al. Among authors: kirschning cj. EMBO Rep. 2015 Dec;16(12):1656-63. doi: 10.15252/embr.201540861. Epub 2015 Nov 6. EMBO Rep. 2015. PMID: 26545385 Free PMC article.
Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia.
Robak OH, Heimesaat MM, Kruglov AA, Prepens S, Ninnemann J, Gutbier B, Reppe K, Hochrein H, Suter M, Kirschning CJ, Marathe V, Buer J, Hornef MW, Schnare M, Schneider P, Witzenrath M, Bereswill S, Steinhoff U, Suttorp N, Sander LE, Chaput C, Opitz B. Robak OH, et al. Among authors: kirschning cj. J Clin Invest. 2018 Aug 1;128(8):3535-3545. doi: 10.1172/JCI97065. Epub 2018 Jul 16. J Clin Invest. 2018. PMID: 29771684 Free PMC article.
Immune hyporeactivity to bacteria and multiple TLR-ligands, yet no response to checkpoint inhibition in patients just after meeting Sepsis-3 criteria.
Bick A, Buys W, Engler A, Madel R, Atia M, Faro F, Westendorf AM, Limmer A, Buer J, Herbstreit F, Kirschning CJ, Peters J. Bick A, et al. Among authors: kirschning cj. PLoS One. 2022 Aug 18;17(8):e0273247. doi: 10.1371/journal.pone.0273247. eCollection 2022. PLoS One. 2022. PMID: 35981050 Free PMC article.
172 results