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A distal regulatory region of a class I human histone deacetylase.
Werbeck ND, Shukla VK, Kunze MBA, Yalinca H, Pritchard RB, Siemons L, Mondal S, Greenwood SOR, Kirkpatrick J, Marson CM, Hansen DF. Werbeck ND, et al. Among authors: kirkpatrick j. Nat Commun. 2020 Jul 31;11(1):3841. doi: 10.1038/s41467-020-17610-w. Nat Commun. 2020. PMID: 32737323 Free PMC article.
An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1 -antitrypsin upon ligand binding.
Nyon MP, Prentice T, Day J, Kirkpatrick J, Sivalingam GN, Levy G, Haq I, Irving JA, Lomas DA, Christodoulou J, Gooptu B, Thalassinos K. Nyon MP, et al. Among authors: kirkpatrick j. Protein Sci. 2015 Aug;24(8):1301-12. doi: 10.1002/pro.2706. Epub 2015 Jul 14. Protein Sci. 2015. PMID: 26011795 Free PMC article.
Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor.
Deckert A, Waudby CA, Wlodarski T, Wentink AS, Wang X, Kirkpatrick JP, Paton JF, Camilloni C, Kukic P, Dobson CM, Vendruscolo M, Cabrita LD, Christodoulou J. Deckert A, et al. Among authors: kirkpatrick jp. Proc Natl Acad Sci U S A. 2016 May 3;113(18):5012-7. doi: 10.1073/pnas.1519124113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27092002 Free PMC article.
Common sequence motifs of nascent chains engage the ribosome surface and trigger factor.
Deckert A, Cassaignau AME, Wang X, Włodarski T, Chan SHS, Waudby CA, Kirkpatrick JP, Vendruscolo M, Cabrita LD, Christodoulou J. Deckert A, et al. Among authors: kirkpatrick jp. Proc Natl Acad Sci U S A. 2021 Dec 28;118(52):e2103015118. doi: 10.1073/pnas.2103015118. Proc Natl Acad Sci U S A. 2021. PMID: 34930833 Free PMC article.
Probing the dynamic stalk region of the ribosome using solution NMR.
Wang X, Kirkpatrick JP, Launay HMM, de Simone A, Häussinger D, Dobson CM, Vendruscolo M, Cabrita LD, Waudby CA, Christodoulou J. Wang X, et al. Among authors: kirkpatrick jp. Sci Rep. 2019 Sep 19;9(1):13528. doi: 10.1038/s41598-019-49190-1. Sci Rep. 2019. PMID: 31537834 Free PMC article.
1,207 results