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UNC2025, a MERTK Small-Molecule Inhibitor, Is Therapeutically Effective Alone and in Combination with Methotrexate in Leukemia Models.
Clin Cancer Res. 2017 Mar 15;23(6):1481-1492. doi: 10.1158/1078-0432.CCR-16-1330. Epub 2016 Sep 20.
Clin Cancer Res. 2017.
PMID: 27649555
Free PMC article.
Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia.
Lee-Sherick AB, Zhang W, Menachof KK, Hill AA, Rinella S, Kirkpatrick G, Page LS, Stashko MA, Jordan CT, Wei Q, Liu J, Zhang D, DeRyckere D, Wang X, Frye S, Earp HS, Graham DK.
Lee-Sherick AB, et al.
Oncotarget. 2015 Mar 30;6(9):6722-36. doi: 10.18632/oncotarget.3156.
Oncotarget. 2015.
PMID: 25762638
Free PMC article.
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Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors.
Zhang W, Zhang D, Stashko MA, DeRyckere D, Hunter D, Kireev D, Miley MJ, Cummings C, Lee M, Norris-Drouin J, Stewart WM, Sather S, Zhou Y, Kirkpatrick G, Machius M, Janzen WP, Earp HS, Graham DK, Frye SV, Wang X.
Zhang W, et al.
J Med Chem. 2013 Dec 12;56(23):9683-92. doi: 10.1021/jm401387j. Epub 2013 Nov 20.
J Med Chem. 2013.
PMID: 24195762
Free PMC article.
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ETV6 mutations define a new cancer predisposition syndrome.
Kirkpatrick G, Noetzli L, Di Paola J, Porter CC.
Kirkpatrick G, et al.
Oncotarget. 2015 Jul 10;6(19):16830-1. doi: 10.18632/oncotarget.4842.
Oncotarget. 2015.
PMID: 26219557
Free PMC article.
No abstract available.
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Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.
Hernandez G, Mills TS, Rabe JL, Chavez JS, Kuldanek S, Kirkpatrick G, Noetzli L, Jubair WK, Zanche M, Myers JR, Stevens BM, Fleenor CJ, Adane B, Dinarello CA, Ashton J, Jordan CT, Di Paola J, Hagman JR, Holers VM, Kuhn KA, Pietras EM.
Hernandez G, et al.
Haematologica. 2020 Mar;105(3):585-597. doi: 10.3324/haematol.2018.197210. Epub 2019 May 17.
Haematologica. 2020.
PMID: 31101752
Free PMC article.
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Outcome after reduced chemotherapy for intermediate-risk neuroblastoma.
Baker DL, Schmidt ML, Cohn SL, Maris JM, London WB, Buxton A, Stram D, Castleberry RP, Shimada H, Sandler A, Shamberger RC, Look AT, Reynolds CP, Seeger RC, Matthay KK; Children’s Oncology Group.
Baker DL, et al.
N Engl J Med. 2010 Sep 30;363(14):1313-23. doi: 10.1056/NEJMoa1001527.
N Engl J Med. 2010.
PMID: 20879880
Free PMC article.
Clinical Trial.
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Bleeding manifestations and management of children with persistent and chronic immune thrombocytopenia: data from the Intercontinental Cooperative ITP Study Group (ICIS).
Neunert CE, Buchanan GR, Imbach P, Bolton-Maggs PH, Bennett CM, Neufeld E, Vesely SK, Adix L, Blanchette VS, Kühne T; Intercontinental Cooperative ITP Study Group Registry II Participants.
Neunert CE, et al.
Blood. 2013 May 30;121(22):4457-62. doi: 10.1182/blood-2012-12-466375. Epub 2013 Apr 2.
Blood. 2013.
PMID: 23550040
Free article.
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