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The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia.
JCI Insight. 2016 Mar;1(3):e85630. doi: 10.1172/jci.insight.85630.
JCI Insight. 2016.
PMID: 27158668
Free PMC article.
Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer.
Cummings CT, Linger RM, Cohen RA, Sather S, Kirkpatrick GD, Davies KD, DeRyckere D, Earp HS, Graham DK.
Cummings CT, et al. Among authors: kirkpatrick gd.
Oncotarget. 2014 Nov 15;5(21):10434-45. doi: 10.18632/oncotarget.2142.
Oncotarget. 2014.
PMID: 25372020
Free PMC article.
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Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status.
Cummings CT, Zhang W, Davies KD, Kirkpatrick GD, Zhang D, DeRyckere D, Wang X, Frye SV, Earp HS, Graham DK.
Cummings CT, et al. Among authors: kirkpatrick gd.
Mol Cancer Ther. 2015 Sep;14(9):2014-22. doi: 10.1158/1535-7163.MCT-15-0116. Epub 2015 Jul 10.
Mol Cancer Ther. 2015.
PMID: 26162689
Free PMC article.
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ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes.
Fisher MH, Kirkpatrick GD, Stevens B, Jones C, Callaghan M, Rajpurkar M, Fulbright J, Cooper MA, Rowley J, Porter CC, Gutierrez-Hartmann A, Jones K, Jordan C, Pietras EM, Di Paola J.
Fisher MH, et al. Among authors: kirkpatrick gd.
JCI Insight. 2020 Sep 17;5(18):e140332. doi: 10.1172/jci.insight.140332.
JCI Insight. 2020.
PMID: 32841218
Free PMC article.
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Recovery and analysis of transcriptome subsets from pooled single-cell RNA-seq libraries.
Riemondy KA, Ransom M, Alderman C, Gillen AE, Fu R, Finlay-Schultz J, Kirkpatrick GD, Di Paola J, Kabos P, Sartorius CA, Hesselberth JR.
Riemondy KA, et al. Among authors: kirkpatrick gd.
Nucleic Acids Res. 2019 Feb 28;47(4):e20. doi: 10.1093/nar/gky1204.
Nucleic Acids Res. 2019.
PMID: 30496484
Free PMC article.
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Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors.
Zhou C, Uluisik R, Rowley JW, David C, Jones CL, Scharer CD, Noetzli L, Fisher MH, Kirkpatrick GD, Bark K, Boss JM, Henry CJ, Pietras EM, Di Paola J, Porter CC.
Zhou C, et al. Among authors: kirkpatrick gd.
Exp Hematol. 2022 Aug-Sep;112-113:24-34. doi: 10.1016/j.exphem.2022.06.002. Epub 2022 Jul 6.
Exp Hematol. 2022.
PMID: 35803545
Free PMC article.
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Hematopoietic recovery following high-dose combined alkylating-agent chemotherapy and autologous bone marrow support in patients in phase-I clinical trials of colony-stimulating factors: G-CSF, GM-CSF, IL-1, IL-2, M-CSF.
Laughlin MJ, Kirkpatrick G, Sabiston N, Peters W, Kurtzberg J.
Laughlin MJ, et al.
Ann Hematol. 1993 Dec;67(6):267-76. doi: 10.1007/BF01696346.
Ann Hematol. 1993.
PMID: 7506580
Clinical Trial.
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