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OTULIN limits cell death and inflammation by deubiquitinating LUBAC.
Heger K, Wickliffe KE, Ndoja A, Zhang J, Murthy A, Dugger DL, Maltzman A, de Sousa E Melo F, Hung J, Zeng Y, Verschueren E, Kirkpatrick DS, Vucic D, Lee WP, Roose-Girma M, Newman RJ, Warming S, Hsiao YC, Kőműves LG, Webster JD, Newton K, Dixit VM. Heger K, et al. Among authors: kirkpatrick ds. Nature. 2018 Jul;559(7712):120-124. doi: 10.1038/s41586-018-0256-2. Epub 2018 Jun 27. Nature. 2018. PMID: 29950720
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Newton K, Matsumoto ML, Wertz IE, Kirkpatrick DS, Lill JR, Tan J, Dugger D, Gordon N, Sidhu SS, Fellouse FA, Komuves L, French DM, Ferrando RE, Lam C, Compaan D, Yu C, Bosanac I, Hymowitz SG, Kelley RF, Dixit VM. Newton K, et al. Among authors: kirkpatrick ds. Cell. 2008 Aug 22;134(4):668-78. doi: 10.1016/j.cell.2008.07.039. Cell. 2008. PMID: 18724939 Free article.
GPS navigation of the protein-stability landscape.
Kirkpatrick DS, Dixit VM. Kirkpatrick DS, et al. Nat Biotechnol. 2009 Jan;27(1):46-8. doi: 10.1038/nbt0109-46. Nat Biotechnol. 2009. PMID: 19131998 No abstract available.
Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals.
Phu L, Izrael-Tomasevic A, Matsumoto ML, Bustos D, Dynek JN, Fedorova AV, Bakalarski CE, Arnott D, Deshayes K, Dixit VM, Kelley RF, Vucic D, Kirkpatrick DS. Phu L, et al. Among authors: kirkpatrick ds. Mol Cell Proteomics. 2011 May;10(5):M110.003756. doi: 10.1074/mcp.M110.003756. Epub 2010 Nov 3. Mol Cell Proteomics. 2011. PMID: 21048196 Free PMC article.
Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling.
Bosanac I, Wertz IE, Pan B, Yu C, Kusam S, Lam C, Phu L, Phung Q, Maurer B, Arnott D, Kirkpatrick DS, Dixit VM, Hymowitz SG. Bosanac I, et al. Among authors: kirkpatrick ds. Mol Cell. 2010 Nov 24;40(4):548-57. doi: 10.1016/j.molcel.2010.10.009. Mol Cell. 2010. PMID: 21095585 Free article.
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling.
Dynek JN, Goncharov T, Dueber EC, Fedorova AV, Izrael-Tomasevic A, Phu L, Helgason E, Fairbrother WJ, Deshayes K, Kirkpatrick DS, Vucic D. Dynek JN, et al. Among authors: kirkpatrick ds. EMBO J. 2010 Dec 15;29(24):4198-209. doi: 10.1038/emboj.2010.300. Epub 2010 Nov 26. EMBO J. 2010. PMID: 21113135 Free PMC article.
107 results