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Past and Future Directions for Research on Cellular Senescence.
Zhu Y, Anastasiadis ZP, Espindola Netto JM, Evans T, Tchkonia T, Kirkland JL. Zhu Y, et al. Among authors: kirkland jl. Cold Spring Harb Perspect Med. 2024 Feb 1;14(2):a041205. doi: 10.1101/cshperspect.a041205. Cold Spring Harb Perspect Med. 2024. PMID: 37734865 Review.
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.
Farr JN, Saul D, Doolittle ML, Kaur J, Rowsey JL, Vos SJ, Froemming MN, Lagnado AB, Zhu Y, Weivoda M, Ikeno Y, Pignolo RJ, Niedernhofer LJ, Robbins PD, Jurk D, Passos JF, LeBrasseur NK, Tchkonia T, Kirkland JL, Monroe DG, Khosla S. Farr JN, et al. Among authors: kirkland jl. J Clin Invest. 2023 Apr 17;133(8):e162519. doi: 10.1172/JCI162519. J Clin Invest. 2023. PMID: 36809340 Free PMC article.
In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell RGG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, LeBrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: kirkland jl. bioRxiv [Preprint]. 2023 Feb 24:2023.02.23.529777. doi: 10.1101/2023.02.23.529777. bioRxiv. 2023. PMID: 36865244 Free PMC article. Updated. Preprint.
A chronic wound model to investigate skin cellular senescence.
Wyles SP, Dashti P, Pirtskhalava T, Tekin B, Inman C, Gomez LS, Lagnado AB, Prata L, Jurk D, Passos JF, Tchkonia T, Kirkland JL. Wyles SP, et al. Among authors: kirkland jl. Aging (Albany NY). 2023 Apr 21;15(8):2852-2862. doi: 10.18632/aging.204667. Epub 2023 Apr 21. Aging (Albany NY). 2023. PMID: 37086260 Free PMC article.
In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell GG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, Lebrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: kirkland jl. Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701. Epub 2023 May 7. Aging (Albany NY). 2023. PMID: 37154858 Free PMC article.
Senescent Cells: A Therapeutic Target in Cardiovascular Diseases.
Suda M, Paul KH, Minamino T, Miller JD, Lerman A, Ellison-Hughes GM, Tchkonia T, Kirkland JL. Suda M, et al. Among authors: kirkland jl. Cells. 2023 May 2;12(9):1296. doi: 10.3390/cells12091296. Cells. 2023. PMID: 37174697 Free PMC article. Review.
Mapping cellular senescence networks in human diabetic foot ulcers.
Yu GT, Monie DD, Khosla S, Tchkonia T, Kirkland JL, Wyles SP. Yu GT, et al. Among authors: kirkland jl. Geroscience. 2024 Feb;46(1):1071-1082. doi: 10.1007/s11357-023-00854-x. Epub 2023 Jun 29. Geroscience. 2024. PMID: 37380899 Free PMC article.
Interleukin-6 in Patients With Heart Failure and Preserved Ejection Fraction.
Alogna A, Koepp KE, Sabbah M, Espindola Netto JM, Jensen MD, Kirkland JL, Lam CSP, Obokata M, Petrie MC, Ridker PM, Sorimachi H, Tchkonia T, Voors A, Redfield MM, Borlaug BA. Alogna A, et al. Among authors: kirkland jl. JACC Heart Fail. 2023 Nov;11(11):1549-1561. doi: 10.1016/j.jchf.2023.06.031. Epub 2023 Aug 9. JACC Heart Fail. 2023. PMID: 37565977 Free PMC article.
353 results