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Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.
Thompson KN, Bonham KS, Ilott NE, Britton GJ, Colmenero P, Bullers SJ, McIver LJ, Ma S, Nguyen LH, Filer A, Brough I, Pearson C, Moussa C, Kumar V, Lam LH, Jackson MA, Pawluk A; Inflammatory Arthritis Microbiome Consortium (IAMC) investigators group; Kiriakidis S, Taylor PC, Wedderburn LR, Marsden B, Young SP, Littman DR, Faith JJ, Pratt AG, Bowness P, Raza K, Powrie F, Huttenhower C; IAMC. Thompson KN, et al. Among authors: kiriakidis s. Sci Transl Med. 2023 Jul 26;15(706):eabn4722. doi: 10.1126/scitranslmed.abn4722. Epub 2023 Jul 26. Sci Transl Med. 2023. PMID: 37494472
Filgotinib for the treatment of rheumatoid arthritis.
Taylor PC, Abdul Azeez M, Kiriakidis S. Taylor PC, et al. Among authors: kiriakidis s. Expert Opin Investig Drugs. 2017 Oct;26(10):1181-1187. doi: 10.1080/13543784.2017.1372422. Epub 2017 Aug 29. Expert Opin Investig Drugs. 2017. PMID: 28838249 Review.
Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.
Kiriakidis S, Hoer SS, Burrows N, Biddlecome G, Khan MN, Thinnes CC, Schofield CJ, Rogers N, Botto M, Paleolog E, Maxwell PH. Kiriakidis S, et al. Kidney Int. 2017 Oct;92(4):900-908. doi: 10.1016/j.kint.2017.03.008. Epub 2017 May 12. Kidney Int. 2017. PMID: 28506759 Free PMC article.
Hypoxia-induced invadopodia formation: a role for β-PIX.
Md Hashim NF, Nicholas NS, Dart AE, Kiriakidis S, Paleolog E, Wells CM. Md Hashim NF, et al. Among authors: kiriakidis s. Open Biol. 2013 Jun 5;3(6):120159. doi: 10.1098/rsob.120159. Open Biol. 2013. PMID: 23740575 Free PMC article.
43 results