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Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients.
Sannino G, Marchetto A, Ranft A, Jabar S, Zacherl C, Alba-Rubio R, Stein S, Wehweck FS, Kiran MM, Hölting TLB, Musa J, Romero-Pérez L, Cidre-Aranaz F, Knott MML, Li J, Jürgens H, Sastre A, Alonso J, Da Silveira W, Hardiman G, Gerke JS, Orth MF, Hartmann W, Kirchner T, Ohmura S, Dirksen U, Grünewald TGP. Sannino G, et al. Among authors: kirchner t. EBioMedicine. 2019 Sep;47:156-162. doi: 10.1016/j.ebiom.2019.08.002. Epub 2019 Aug 16. EBioMedicine. 2019. PMID: 31427232 Free PMC article.
Acute stress enhances the expression of neuroprotection- and neurogenesis-associated genes in the hippocampus of a mouse restraint model.
Sannino G, Pasqualini L, Ricciardelli E, Montilla P, Soverchia L, Ruggeri B, Falcinelli S, Renzi A, Ludka C, Kirchner T, Grünewald TG, Ciccocioppo R, Ubaldi M, Hardiman G. Sannino G, et al. Among authors: kirchner t. Oncotarget. 2016 Feb 23;7(8):8455-65. doi: 10.18632/oncotarget.7225. Oncotarget. 2016. PMID: 26863456 Free PMC article.
Human HLA-A*02:01/CHM1+ allo-restricted T cell receptor transgenic CD8+ T cells specifically inhibit Ewing sarcoma growth in vitro and in vivo.
Blaeschke F, Thiel U, Kirschner A, Thiede M, Rubio RA, Schirmer D, Kirchner T, Richter GHS, Mall S, Klar R, Riddell S, Busch DH, Krackhardt A, Grunewald TG, Burdach S. Blaeschke F, et al. Among authors: kirchner t. Oncotarget. 2016 Jul 12;7(28):43267-43280. doi: 10.18632/oncotarget.9218. Oncotarget. 2016. PMID: 27281613 Free PMC article.
EWS-FLI1-mediated suppression of the RAS-antagonist Sprouty 1 (SPRY1) confers aggressiveness to Ewing sarcoma.
Cidre-Aranaz F, Grünewald TG, Surdez D, García-García L, Carlos Lázaro J, Kirchner T, González-González L, Sastre A, García-Miguel P, López-Pérez SE, Monzón S, Delattre O, Alonso J. Cidre-Aranaz F, et al. Among authors: kirchner t. Oncogene. 2017 Feb 9;36(6):766-776. doi: 10.1038/onc.2016.244. Epub 2016 Jul 4. Oncogene. 2017. PMID: 27375017
768 results