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Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease.
Chinthapatla R, Sotoudegan M, Srivastava P, Anderson TK, Moustafa IM, Passow KT, Kennelly SA, Moorthy R, Dulin D, Feng JY, Harki DA, Kirchdoerfer RN, Cameron CE, Arnold JJ. Chinthapatla R, et al. Among authors: kirchdoerfer rn. Nucleic Acids Res. 2023 Jan 11;51(1):315-336. doi: 10.1093/nar/gkac1177. Nucleic Acids Res. 2023. PMID: 36546762 Free PMC article.
Organization of the influenza virus replication machinery.
Moeller A, Kirchdoerfer RN, Potter CS, Carragher B, Wilson IA. Moeller A, et al. Among authors: kirchdoerfer rn. Science. 2012 Dec 21;338(6114):1631-4. doi: 10.1126/science.1227270. Epub 2012 Nov 22. Science. 2012. PMID: 23180774 Free PMC article.
Structure of the Reston ebolavirus VP30 C-terminal domain.
Clifton MC, Kirchdoerfer RN, Atkins K, Abendroth J, Raymond A, Grice R, Barnes S, Moen S, Lorimer D, Edwards TE, Myler PJ, Saphire EO. Clifton MC, et al. Among authors: kirchdoerfer rn. Acta Crystallogr F Struct Biol Commun. 2014 Apr;70(Pt 4):457-60. doi: 10.1107/S2053230X14003811. Epub 2014 Mar 25. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24699737 Free PMC article.
Crystal structures of a quorum-quenching antibody.
Debler EW, Kaufmann GF, Kirchdoerfer RN, Mee JM, Janda KD, Wilson IA. Debler EW, et al. Among authors: kirchdoerfer rn. J Mol Biol. 2007 May 18;368(5):1392-402. doi: 10.1016/j.jmb.2007.02.081. Epub 2007 Mar 6. J Mol Biol. 2007. PMID: 17400249 Free PMC article.
From structure to sequence: Antibody discovery using cryoEM.
Antanasijevic A, Bowman CA, Kirchdoerfer RN, Cottrell CA, Ozorowski G, Upadhyay AA, Cirelli KM, Carnathan DG, Enemuo CA, Sewall LM, Nogal B, Zhao F, Groschel B, Schief WR, Sok D, Silvestri G, Crotty S, Bosinger SE, Ward AB. Antanasijevic A, et al. Among authors: kirchdoerfer rn. Sci Adv. 2022 Jan 21;8(3):eabk2039. doi: 10.1126/sciadv.abk2039. Epub 2022 Jan 19. Sci Adv. 2022. PMID: 35044813 Free PMC article.
The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
King LB, Fusco ML, Flyak AI, Ilinykh PA, Huang K, Gunn B, Kirchdoerfer RN, Hastie KM, Sangha AK, Meiler J, Alter G, Bukreyev A, Crowe JE Jr, Saphire EO. King LB, et al. Among authors: kirchdoerfer rn. Cell Host Microbe. 2018 Jan 10;23(1):101-109.e4. doi: 10.1016/j.chom.2017.12.003. Cell Host Microbe. 2018. PMID: 29324225 Free PMC article.
Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase.
Chien M, Anderson TK, Jockusch S, Tao C, Kumar S, Li X, Russo JJ, Kirchdoerfer RN, Ju J. Chien M, et al. Among authors: kirchdoerfer rn. bioRxiv [Preprint]. 2020 Mar 20:2020.03.18.997585. doi: 10.1101/2020.03.18.997585. bioRxiv. 2020. PMID: 32511320 Free PMC article. Updated. Preprint.
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