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Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries.
Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Lee H, Kipnis J, Tannenbaum A, Van Nostrand WE, Benveniste H. Chen X, et al. Among authors: kipnis j. Nat Aging. 2022 Mar;2(3):214-223. doi: 10.1038/s43587-022-00181-4. Epub 2022 Mar 7. Nat Aging. 2022. PMID: 36199752 Free PMC article. No abstract available.
Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease.
Da Mesquita S, Louveau A, Vaccari A, Smirnov I, Cornelison RC, Kingsmore KM, Contarino C, Onengut-Gumuscu S, Farber E, Raper D, Viar KE, Powell RD, Baker W, Dabhi N, Bai R, Cao R, Hu S, Rich SS, Munson JM, Lopes MB, Overall CC, Acton ST, Kipnis J. Da Mesquita S, et al. Among authors: kipnis j. Nature. 2018 Aug;560(7717):185-191. doi: 10.1038/s41586-018-0368-8. Epub 2018 Jul 25. Nature. 2018. PMID: 30046111 Free PMC article.
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid.
Drieu A, Du S, Storck SE, Rustenhoven J, Papadopoulos Z, Dykstra T, Zhong F, Kim K, Blackburn S, Mamuladze T, Harari O, Karch CM, Bateman RJ, Perrin R, Farlow M, Chhatwal J; Dominantly Inherited Alzheimer Network; Hu S, Randolph GJ, Smirnov I, Kipnis J. Drieu A, et al. Among authors: kipnis j. Nature. 2022 Nov;611(7936):585-593. doi: 10.1038/s41586-022-05397-3. Epub 2022 Nov 9. Nature. 2022. PMID: 36352225 Free PMC article.
Brain borders at the central stage of neuroimmunology.
Rustenhoven J, Kipnis J. Rustenhoven J, et al. Among authors: kipnis j. Nature. 2022 Dec;612(7940):417-429. doi: 10.1038/s41586-022-05474-7. Epub 2022 Dec 14. Nature. 2022. PMID: 36517712 Free PMC article. Review.
Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Chen X, Firulyova M, Manis M, Herz J, Smirnov I, Aladyeva E, Wang C, Bao X, Finn MB, Hu H, Shchukina I, Kim MW, Yuede CM, Kipnis J, Artyomov MN, Ulrich JD, Holtzman DM. Chen X, et al. Among authors: kipnis j. Nature. 2023 Mar;615(7953):668-677. doi: 10.1038/s41586-023-05788-0. Epub 2023 Mar 8. Nature. 2023. PMID: 36890231 Free PMC article.
Identification of direct connections between the dura and the brain.
Smyth LCD, Xu D, Okar SV, Dykstra T, Rustenhoven J, Papadopoulos Z, Bhasiin K, Kim MW, Drieu A, Mamuladze T, Blackburn S, Gu X, Gaitán MI, Nair G, Storck SE, Du S, White MA, Bayguinov P, Smirnov I, Dikranian K, Reich DS, Kipnis J. Smyth LCD, et al. Among authors: kipnis j. Nature. 2024 Mar;627(8002):165-173. doi: 10.1038/s41586-023-06993-7. Epub 2024 Feb 7. Nature. 2024. PMID: 38326613
174 results