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A Placebo-controlled double-blinded test of the biodiversity hypothesis of immune-mediated diseases: Environmental microbial diversity elicits changes in cytokines and increase in T regulatory cells in young children.
Roslund MI, Parajuli A, Hui N, Puhakka R, Grönroos M, Soininen L, Nurminen N, Oikarinen S, Cinek O, Kramná L, Schroderus AM, Laitinen OH, Kinnunen T, Hyöty H, Sinkkonen A; ADELE research group. Roslund MI, et al. Among authors: kinnunen t. Ecotoxicol Environ Saf. 2022 Sep 1;242:113900. doi: 10.1016/j.ecoenv.2022.113900. Epub 2022 Aug 3. Ecotoxicol Environ Saf. 2022. PMID: 35930838 Free article. Clinical Trial.
Circulating CXCR5+PD-1+ICOS+ Follicular T Helper Cells Are Increased Close to the Diagnosis of Type 1 Diabetes in Children With Multiple Autoantibodies.
Viisanen T, Ihantola EL, Näntö-Salonen K, Hyöty H, Nurminen N, Selvenius J, Juutilainen A, Moilanen L, Pihlajamäki J, Veijola R, Toppari J, Knip M, Ilonen J, Kinnunen T. Viisanen T, et al. Among authors: kinnunen t. Diabetes. 2017 Feb;66(2):437-447. doi: 10.2337/db16-0714. Epub 2016 Oct 10. Diabetes. 2017. PMID: 28108610
Biodiversity intervention enhances immune regulation and health-associated commensal microbiota among daycare children.
Roslund MI, Puhakka R, Grönroos M, Nurminen N, Oikarinen S, Gazali AM, Cinek O, Kramná L, Siter N, Vari HK, Soininen L, Parajuli A, Rajaniemi J, Kinnunen T, Laitinen OH, Hyöty H, Sinkkonen A; ADELE research group. Roslund MI, et al. Among authors: kinnunen t. Sci Adv. 2020 Oct 14;6(42):eaba2578. doi: 10.1126/sciadv.aba2578. Print 2020 Oct. Sci Adv. 2020. PMID: 33055153 Free PMC article. Clinical Trial.
Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression.
Schroderus AM, Poorbaugh J, McElyea S, Beasley S, Zhang L, Näntö-Salonen K, Rintamäki R, Pihlajamäki J, Knip M, Veijola R, Toppari J, Ilonen J, Benschop RJ, Kinnunen T. Schroderus AM, et al. Among authors: kinnunen t. Front Immunol. 2023 Jun 21;14:1157265. doi: 10.3389/fimmu.2023.1157265. eCollection 2023. Front Immunol. 2023. PMID: 37415982 Free PMC article.
B cell helper T cells and type 1 diabetes.
Vandamme C, Kinnunen T. Vandamme C, et al. Among authors: kinnunen t. Scand J Immunol. 2020 Oct;92(4):e12943. doi: 10.1111/sji.12943. Scand J Immunol. 2020. PMID: 32697399 Free PMC article. Review.
206 results