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Fatty acid synthesis is a therapeutic target in human liposarcoma.
Olsen AM, Eisenberg BL, Kuemmerle NB, Flanagan AJ, Morganelli PM, Lombardo PS, Swinnen JV, Kinlaw WB. Olsen AM, et al. Among authors: kinlaw wb. Int J Oncol. 2010 May;36(5):1309-14. doi: 10.3892/ijo_00000616. Int J Oncol. 2010. PMID: 20372807 Free PMC article.
Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1.
Moyer BJ, Rojas IY, Kerley-Hamilton JS, Hazlett HF, Nemani KV, Trask HW, West RJ, Lupien LE, Collins AJ, Ringelberg CS, Gimi B, Kinlaw WB 3rd, Tomlinson CR. Moyer BJ, et al. Among authors: kinlaw wb 3rd. Toxicol Appl Pharmacol. 2016 Jun 1;300:13-24. doi: 10.1016/j.taap.2016.03.011. Epub 2016 Mar 25. Toxicol Appl Pharmacol. 2016. PMID: 27020609 Free PMC article.
Lipoprotein lipase links dietary fat to solid tumor cell proliferation.
Kuemmerle NB, Rysman E, Lombardo PS, Flanagan AJ, Lipe BC, Wells WA, Pettus JR, Froehlich HM, Memoli VA, Morganelli PM, Swinnen JV, Timmerman LA, Chaychi L, Fricano CJ, Eisenberg BL, Coleman WB, Kinlaw WB. Kuemmerle NB, et al. Among authors: kinlaw wb. Mol Cancer Ther. 2011 Mar;10(3):427-36. doi: 10.1158/1535-7163.MCT-10-0802. Epub 2011 Jan 31. Mol Cancer Ther. 2011. PMID: 21282354 Free PMC article.
AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells.
Hampsch RA, Wells JD, Traphagen NA, McCleery CF, Fields JL, Shee K, Dillon LM, Pooler DB, Lewis LD, Demidenko E, Huang YH, Marotti JD, Goen AE, Kinlaw WB, Miller TW. Hampsch RA, et al. Among authors: kinlaw wb. Clin Cancer Res. 2020 Jul 15;26(14):3707-3719. doi: 10.1158/1078-0432.CCR-20-0269. Epub 2020 Apr 22. Clin Cancer Res. 2020. PMID: 32321715 Free PMC article.
59 results