Kimani S - Search Results

1

Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins.

Sahm BDB, Peres J, Rezende-Teixeira P, Santos EA, Branco PC, Bauermeister A, Kimani S, Moreira EA, Bisi-Alves R, Bellis C, Mlaza M, Jimenez PC, Lopes NP, Machado-Santelli GM, Prince S, Costa-Lotufo LV. Sahm BDB, et al. Among authors: kimani s. Front Chem. 2020 Mar 3;8:110. doi: 10.3389/fchem.2020.00110. eCollection 2020. Front Chem. 2020. PMID: 32195221 Free PMC article.

2

Managing sarcoma: where have we come from and where are we going?

Bleloch JS, Ballim RD, Kimani S, Parkes J, Panieri E, Willmer T, Prince S. Bleloch JS, et al. Among authors: kimani s. Ther Adv Med Oncol. 2017 Oct;9(10):637-659. doi: 10.1177/1758834017728927. Epub 2017 Sep 20. Ther Adv Med Oncol. 2017. PMID: 28974986 Free PMC article. Review.

3

The palladacycle complex AJ-5 induces apoptotic cell death while reducing autophagic flux in rhabdomyosarcoma cells.

Bleloch JS, du Toit A, Gibhard L, Kimani S, Ballim RD, Lee M, Blanckenberg A, Mapolie S, Wiesner L, Loos B, Prince S. Bleloch JS, et al. Among authors: kimani s. Cell Death Discov. 2019 Jan 28;5:60. doi: 10.1038/s41420-019-0139-9. eCollection 2019. Cell Death Discov. 2019. PMID: 30701092 Free PMC article.

4

The palladacycle, BTC2, exhibits anti-breast cancer and breast cancer stem cell activity.

Kimani S, Chakraborty S, Irene I, de la Mare J, Edkins A, du Toit A, Loos B, Blanckenberg A, Van Niekerk A, Costa-Lotufo LV, ArulJothi KN, Mapolie S, Prince S. Kimani S, et al. Biochem Pharmacol. 2021 Aug;190:114598. doi: 10.1016/j.bcp.2021.114598. Epub 2021 May 9. Biochem Pharmacol. 2021. PMID: 33979647

5

The diaryl-imidazopyridazine anti-plasmodial compound, MMV652103, exhibits anti-breast cancer activity.

Neumann-Mufweba A, Kimani S, Khan SF, Chibale K, Prince S. Neumann-Mufweba A, et al. Among authors: kimani s. EXCLI J. 2022 Apr 4;21:656-679. doi: 10.17179/excli2021-4323. eCollection 2022. EXCLI J. 2022. PMID: 35651652 Free PMC article.

6

DNA-binding affinity and molecular docking studies of the PEGylated binuclear palladacycle, BTC2, an efficient metallodrug against triple-negative breast cancer.

van Niekerk A, Blanckenberg A, Kimani S, Chakraborty S, Prince S, Chellan P, Mapolie S. van Niekerk A, et al. Among authors: kimani s. J Inorg Biochem. 2023 Jun;243:112191. doi: 10.1016/j.jinorgbio.2023.112191. Epub 2023 Mar 12. J Inorg Biochem. 2023. PMID: 36996694

7

The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.

Weber BW, Kimani SW, Varsani A, Cowan DA, Hunter R, Venter GA, Gumbart JC, Sewell BT. Weber BW, et al. J Biol Chem. 2013 Oct 4;288(40):28514-23. doi: 10.1074/jbc.M113.503284. Epub 2013 Aug 14. J Biol Chem. 2013. PMID: 23946488 Free PMC article.

8

The quaternary structure of the amidase from Geobacillus pallidus RAPc8 is revealed by its crystal packing.

Agarkar VB, Kimani SW, Cowan DA, Sayed MF, Sewell BT. Agarkar VB, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt 12):1174-8. doi: 10.1107/S1744309106043855. Epub 2006 Nov 4. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17142891 Free PMC article.

9

Structure of an aliphatic amidase from Geobacillus pallidus RAPc8.

Kimani SW, Agarkar VB, Cowan DA, Sayed MF, Sewell BT. Kimani SW, et al. Acta Crystallogr D Biol Crystallogr. 2007 Oct;63(Pt 10):1048-58. doi: 10.1107/S090744490703836X. Epub 2007 Sep 19. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17881822 Free article.

10

The Effect of Stigma on Family Planning and HIV Pre-exposure Prophylaxis Decisions of Young Women Accessing Post-Abortion Care in Kenya.

Zia Y, Etyang L, Mwangi M, Njiru R, Mogaka F, June L, Njeru I, Makoyo J, Kimani S, Ngure K, Wanyama I, Bukusi E, Nyerere B, Nyamwaro C, Mugo N, Heffron R; PrEDIRA team. Zia Y, et al. Among authors: kimani s. AIDS Behav. 2024 Mar 7. doi: 10.1007/s10461-024-04274-6. Online ahead of print. AIDS Behav. 2024. PMID: 38451448

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