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Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth.
Kim W, Lee S, Kim HS, Song M, Cha YH, Kim YH, Shin J, Lee ES, Joo Y, Song JJ, Choi EJ, Choi JW, Lee J, Kang M, Yook JI, Lee MG, Kim YS, Paik S, Kim HH. Kim W, et al. Among authors: kim yh, kim hh, kim ys, kim hs. Genome Res. 2018 Jan 11;28(3):374-82. doi: 10.1101/gr.223891.117. Online ahead of print. Genome Res. 2018. PMID: 29326299 Free PMC article.
Genome engineering in human cells.
Song M, Kim YH, Kim JS, Kim H. Song M, et al. Among authors: kim yh, kim h, kim js. Methods Enzymol. 2014;546:93-118. doi: 10.1016/B978-0-12-801185-0.00005-2. Methods Enzymol. 2014. PMID: 25398337 Review.
Sniper2L is a high-fidelity Cas9 variant with high activity.
Kim YH, Kim N, Okafor I, Choi S, Min S, Lee J, Bae SM, Choi K, Choi J, Harihar V, Kim Y, Kim JS, Kleinstiver BP, Lee JK, Ha T, Kim HH. Kim YH, et al. Among authors: kim hh, kim n, kim js, kim y. Nat Chem Biol. 2023 Aug;19(8):972-980. doi: 10.1038/s41589-023-01279-5. Epub 2023 Mar 9. Nat Chem Biol. 2023. PMID: 36894722 Free PMC article.
Directed evolution of CRISPR-Cas9 to increase its specificity.
Lee JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, Lee K, Jung I, Kim D, Kim S, Kim JS. Lee JK, et al. Among authors: kim yh, kim d, kim s, kim js. Nat Commun. 2018 Aug 6;9(1):3048. doi: 10.1038/s41467-018-05477-x. Nat Commun. 2018. PMID: 30082838 Free PMC article.
12,458 results
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