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The alpha-methylene-gamma-butyrolactone moiety in dehydrocostus lactone is responsible for cytoprotective heme oxygenase-1 expression through activation of the nuclear factor E2-related factor 2 in HepG2 cells.
Jeong GS, Pae HO, Jeong SO, Kim YC, Kwon TO, Lee HS, Kim NS, Park SD, Chung HT. Jeong GS, et al. Among authors: kim ns, kim yc. Eur J Pharmacol. 2007 Jun 22;565(1-3):37-44. doi: 10.1016/j.ejphar.2007.02.053. Epub 2007 Mar 7. Eur J Pharmacol. 2007. PMID: 17391667
3,219 results