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Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery.
Hatit MZC, Dobrowolski CN, Lokugamage MP, Loughrey D, Ni H, Zurla C, Da Silva Sanchez AJ, Radmand A, Huayamares SG, Zenhausern R, Paunovska K, Peck HE, Kim J, Sato M, Feldman JI, Rivera MA, Cristian A, Kim Y, Santangelo PJ, Dahlman JE. Hatit MZC, et al. Among authors: kim j, kim y. Nat Chem. 2023 Apr;15(4):508-515. doi: 10.1038/s41557-023-01138-9. Epub 2023 Mar 2. Nat Chem. 2023. PMID: 36864143
Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo.
Ni H, Hatit MZC, Zhao K, Loughrey D, Lokugamage MP, Peck HE, Cid AD, Muralidharan A, Kim Y, Santangelo PJ, Dahlman JE. Ni H, et al. Among authors: kim y. Nat Commun. 2022 Aug 15;13(1):4766. doi: 10.1038/s41467-022-32281-5. Nat Commun. 2022. PMID: 35970837 Free PMC article.
HDL-mimetic PLGA nanoparticle to target atherosclerosis plaque macrophages.
Sanchez-Gaytan BL, Fay F, Lobatto ME, Tang J, Ouimet M, Kim Y, van der Staay SE, van Rijs SM, Priem B, Zhang L, Fisher EA, Moore KJ, Langer R, Fayad ZA, Mulder WJ. Sanchez-Gaytan BL, et al. Among authors: kim y. Bioconjug Chem. 2015 Mar 18;26(3):443-51. doi: 10.1021/bc500517k. Epub 2015 Feb 13. Bioconjug Chem. 2015. PMID: 25650634 Free PMC article.
Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis.
Kim Y, Lobatto ME, Kawahara T, Lee Chung B, Mieszawska AJ, Sanchez-Gaytan BL, Fay F, Senders ML, Calcagno C, Becraft J, Tun Saung M, Gordon RE, Stroes ES, Ma M, Farokhzad OC, Fayad ZA, Mulder WJ, Langer R. Kim Y, et al. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1078-83. doi: 10.1073/pnas.1322725111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395808 Free PMC article.
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