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Tramadol regulates the activation of human platelets via Rac but not Rho/Rho-kinase.
Iida H, Onuma T, Nakashima D, Mizutani D, Hori T, Ueda K, Hioki T, Kim W, Enomoto Y, Doi T, Matsushima-Nishiwaki R, Yamaguchi S, Tachi J, Tanabe K, Ogura S, Iwama T, Kozawa O, Tokuda H. Iida H, et al. Among authors: kim w. PLoS One. 2023 Jan 13;18(1):e0279011. doi: 10.1371/journal.pone.0279011. eCollection 2023. PLoS One. 2023. PMID: 36638092 Free PMC article.
Enhancement by HSP90 inhibitor of PGD2-stimulated HSP27 induction in osteoblasts: Suppression of SAPK/JNK and p38 MAP kinase.
Kim W, Tokuda H, Kawabata T, Fujita K, Sakai G, Nakashima D, Tachi J, Kuroyanagi G, Matsushima-Nishiwaki R, Tanabe K, Otsuka T, Iida H, Kozawa O. Kim W, et al. Prostaglandins Other Lipid Mediat. 2019 Aug;143:106327. doi: 10.1016/j.prostaglandins.2019.03.002. Epub 2019 Apr 1. Prostaglandins Other Lipid Mediat. 2019. PMID: 30946899
Upregulation of TGF-β-induced HSP27 by HSP90 inhibitors in osteoblasts.
Kuroyanagi G, Tokuda H, Fujita K, Kawabata T, Sakai G, Kim W, Hioki T, Tachi J, Matsushima-Nishiwaki R, Otsuka T, Iida H, Kozawa O. Kuroyanagi G, et al. Among authors: kim w. BMC Musculoskelet Disord. 2022 May 26;23(1):495. doi: 10.1186/s12891-022-05419-1. BMC Musculoskelet Disord. 2022. PMID: 35619094 Free PMC article.
Tramadol enhances PGF-stimulated osteoprotegerin synthesis in osteoblasts.
Kim W, Tanabe K, Kuroyanagi G, Matsushima-Nishiwaki R, Fujita K, Kawabata T, Sakai G, Tachi J, Hioki T, Nakashima D, Yamaguchi S, Otsuka T, Tokuda H, Kozawa O, Iida H. Kim W, et al. Heliyon. 2020 Aug 24;6(8):e04779. doi: 10.1016/j.heliyon.2020.e04779. eCollection 2020 Aug. Heliyon. 2020. PMID: 32904295 Free PMC article.
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