A novel peripheral cannabinoid 1 receptor antagonist, AJ5012, improves metabolic outcomes and suppresses adipose tissue inflammation in obese mice.
Han JH, Shin H, Park JY, Rho JG, Son DH, Kim KW, Seong JK, Yoon SH, Kim W.
Han JH, et al. Among authors: kim w, kim kw.
FASEB J. 2019 Mar;33(3):4314-4326. doi: 10.1096/fj.201801152RR. Epub 2018 Dec 19.
FASEB J. 2019.
PMID: 30566396
Our findings identified AJ5012 as a novel peripheral CB1R antagonist and suggest that peripheral CB1R blockade might break the links between insulin resistance and adipose tissue inflammation.-Han, J. H., Shin, H., Park, J.-Y., Rho, J. G., Son, D. H., Kim, K. W., Se …
Our findings identified AJ5012 as a novel peripheral CB1R antagonist and suggest that peripheral CB1R blockade might break the links between …