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The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha.
Hong MN, Nam KY, Kim KK, Kim SY, Kim I. Hong MN, et al. Among authors: kim kk, kim sy, kim i. Cell Stress Chaperones. 2016 May;21(3):485-97. doi: 10.1007/s12192-016-0677-5. Epub 2016 Feb 12. Cell Stress Chaperones. 2016. PMID: 26873011 Free PMC article.
Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation.
Kim SY, Hong M, Heo SH, Park S, Kwon TK, Sung YH, Oh Y, Lee S, Yi GS, Kim I. Kim SY, et al. Among authors: kim i. Mol Carcinog. 2018 Nov;57(11):1492-1506. doi: 10.1002/mc.22872. Epub 2018 Jul 19. Mol Carcinog. 2018. PMID: 29964331
Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas.
Lee HM, Joh JW, Seo SR, Kim WT, Kim MK, Choi HS, Kim SY, Jang YJ, Sinn DH, Choi GS, Kim JM, Kwon CHD, Chang HJ, Kim DS, Ryu CJ. Lee HM, et al. Among authors: kim ds, kim jm, kim sy, kim wt, kim mk. Sci Rep. 2017 Oct 16;7(1):13201. doi: 10.1038/s41598-017-13501-1. Sci Rep. 2017. PMID: 29038587 Free PMC article.
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