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Mechanisms of CD40-dependent cDC1 licensing beyond costimulation.
Wu R, Ohara RA, Jo S, Liu TT, Ferris ST, Ou F, Kim S, Theisen DJ, Anderson DA 3rd, Wong BW, Gershon T, Schreiber RD, Murphy TL, Murphy KM. Wu R, et al. Among authors: kim s. Nat Immunol. 2022 Nov;23(11):1536-1550. doi: 10.1038/s41590-022-01324-w. Epub 2022 Oct 21. Nat Immunol. 2022. PMID: 36271147 Free PMC article.
An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development.
Bagadia P, Huang X, Liu TT, Durai V, Grajales-Reyes GE, Nitschké M, Modrusan Z, Granja JM, Satpathy AT, Briseño CG, Gargaro M, Iwata A, Kim S, Chang HY, Shaw AS, Murphy TL, Murphy KM. Bagadia P, et al. Among authors: kim s. Nat Immunol. 2019 Sep;20(9):1174-1185. doi: 10.1038/s41590-019-0449-3. Epub 2019 Aug 12. Nat Immunol. 2019. PMID: 31406377 Free PMC article.
Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis.
Huang X, Ferris ST, Kim S, Choudhary MNK, Belk JA, Fan C, Qi Y, Sudan R, Xia Y, Desai P, Chen J, Ly N, Shi Q, Bagadia P, Liu T, Guilliams M, Egawa T, Colonna M, Diamond MS, Murphy TL, Satpathy AT, Wang T, Murphy KM. Huang X, et al. Among authors: kim s. Immunity. 2021 Jul 13;54(7):1417-1432.e7. doi: 10.1016/j.immuni.2021.04.015. Epub 2021 May 17. Immunity. 2021. PMID: 34004142 Free PMC article.
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication.
Gargaro M, Scalisi G, Manni G, Briseño CG, Bagadia P, Durai V, Theisen DJ, Kim S, Castelli M, Xu CA, Meyer Zu Hörste G, Servillo G, Della Fazia MA, Mencarelli G, Ricciuti D, Padiglioni E, Giacchè N, Colliva C, Pellicciari R, Calvitti M, Zelante T, Fuchs D, Orabona C, Boon L, Bessede A, Colonna M, Puccetti P, Murphy TL, Murphy KM, Fallarino F. Gargaro M, et al. Among authors: kim s. Immunity. 2022 Jun 14;55(6):1032-1050.e14. doi: 10.1016/j.immuni.2022.05.013. Immunity. 2022. PMID: 35704993 Free PMC article.
Ablation of cDC2 development by triple mutations within the Zeb2 enhancer.
Liu TT, Kim S, Desai P, Kim DH, Huang X, Ferris ST, Wu R, Ou F, Egawa T, Van Dyken SJ, Diamond MS, Johnson PF, Kubo M, Murphy TL, Murphy KM. Liu TT, et al. Among authors: kim dh, kim s. Nature. 2022 Jul;607(7917):142-148. doi: 10.1038/s41586-022-04866-z. Epub 2022 Jun 22. Nature. 2022. PMID: 35732734 Free PMC article.
WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis.
Ferris ST, Liu T, Chen J, Ohara RA, Ou F, Wu R, Kim S, Murphy TL, Murphy KM. Ferris ST, et al. Among authors: kim s. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2219956120. doi: 10.1073/pnas.2219956120. Epub 2023 Mar 20. Proc Natl Acad Sci U S A. 2023. PMID: 36940342 Free PMC article.
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