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Page 1
Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.
Almeida ARM, Neto JL, Cachucho A, Euzébio M, Meng X, Kim R, Fernandes MB, Raposo B, Oliveira ML, Ribeiro D, Fragoso R, Zenatti PP, Soares T, de Matos MR, Corrêa JR, Duque M, Roberts KG, Gu Z, Qu C, Pereira C, Pyne S, Pyne NJ, Barreto VM, Bernard-Pierrot I, Clappier E, Mullighan CG, Grosso AR, Yunes JA, Barata JT. Almeida ARM, et al. Among authors: kim r. Nat Commun. 2021 Dec 14;12(1):7268. doi: 10.1038/s41467-021-27197-5. Nat Commun. 2021. PMID: 34907175 Free PMC article.
Differential activation of basal and IL-7-induced PI3K/Akt/mTOR and JAK/STAT5 signaling distinguishes pediatric from adult acute lymphoblastic leukemia.
Fernandes MB, Gomes AM, Oliveira ML, Caldas J, Lúcio P, Kim R, Caye-Eude A, Pereira F, De Sousa AB, De Stefano A, Follo MY, Soares MV, Lacerda JF, Desterro J, Cavé H, Clappier E, Duarte X, Ribeiro P, Barata JT. Fernandes MB, et al. Among authors: kim r. Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2023.284102. Online ahead of print. Haematologica. 2024. PMID: 38654666 Free article.
Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation.
Kim R, Boissel N, Touzart A, Leguay T, Thonier F, Thomas X, Raffoux E, Huguet F, Villarese P, Fourrage C, Passini L, Hunault M, Lepretre S, Chevallier P, Braun T, Lhéritier V, Chantepie S, Maury S, Escoffre M, Tavernier E, Chalandon Y, Graux C, Macintyre E, Ifrah N, Asnafi V, Dombret H, Lhermitte L; on behalf the GRAALL group. Kim R, et al. Leukemia. 2020 Jul;34(7):1730-1740. doi: 10.1038/s41375-019-0685-4. Epub 2020 Jan 28. Leukemia. 2020. PMID: 31992840 Clinical Trial.
Ikaros deficiency is associated with aggressive BCR-ABL1 B-cell precursor acute lymphoblastic leukemia independent of the lineage and developmental origin.
Simand C, Keime C, Cayé A, Arfeuille C, Passet M, Kim R, Cavé H, Clappier E, Kastner P, Chan S, Heizmann B. Simand C, et al. Among authors: kim r. Haematologica. 2022 Jan 1;107(1):316-320. doi: 10.3324/haematol.2021.279125. Haematologica. 2022. PMID: 34587720 Free PMC article. No abstract available.
Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation.
Boy M, Bisio V, Zhao LP, Guidez F, Schell B, Lereclus E, Henry G, Villemonteix J, Rodrigues-Lima F, Gagne K, Retiere C, Larcher L, Kim R, Clappier E, Sebert M, Mekinian A, Fain O, Caignard A, Espeli M, Balabanian K, Toubert A, Fenaux P, Ades L, Dulphy N. Boy M, et al. Among authors: kim r. Nat Commun. 2023 Feb 3;14(1):588. doi: 10.1038/s41467-023-36193-w. Nat Commun. 2023. PMID: 36737440 Free PMC article.
IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition.
Courtois L, Cabannes-Hamy A, Kim R, Delecourt M, Pinton A, Charbonnier G, Feroul M, Smith C, Tueur G, Pivert C, Balducci E, Simonin M, Angel LH, Spicuglia S, Boissel N, Andrieu GP, Asnafi V, Rousselot P, Lhermitte L. Courtois L, et al. Among authors: kim r. Blood. 2023 Jul 13;142(2):158-171. doi: 10.1182/blood.2022017948. Blood. 2023. PMID: 37023368
Outcome and clinicophenotypical features of acute lymphoblastic leukemia/lymphoblastic lymphoma with cutaneous involvement: A multicenter case series.
Bontoux C, De Masson A, Boccara O, Bodemer C, Fraitag S, Balme B, Franck N, Carlotti A, Comoz F, Verneuil L, Brasme JF, Duplan M, Croué A, Templier I, Beltraminelli H, Dereure O, Szablewski V, Thevenin C, Boulinguez S, Viraben R, Tournier E, Lamant L, Ortonne N, Ingen-Housz-Oro S, Beckerich F, Grange F, Durlach A, Amatore F, Frouin E, McIntyre E, Asnafi V, Kim R, Clappier E, Soulier J, Boissel N, Dombret H, Bagot M, Battistella M; Groupe Français d’Etude des Lymphomes Cutanés (GFELC). Bontoux C, et al. Among authors: kim r. J Am Acad Dermatol. 2020 Oct;83(4):1166-1170. doi: 10.1016/j.jaad.2020.01.058. Epub 2020 Jan 31. J Am Acad Dermatol. 2020. PMID: 32007515 No abstract available.
Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL.
Passet M, Kim R, Gachet S, Sigaux F, Chaumeil J, Galland A, Sexton T, Quentin S, Hernandez L, Larcher L, Bergugnat H, Ye T, Karasu N, Caye A, Heizmann B, Duluc I, Chevallier P, Rousselot P, Huguet F, Leguay T, Hunault M, Pflumio F, Freund JN, Lobry C, Lhéritier V, Dombret H, Domon-Dell C, Soulier J, Boissel N, Clappier E. Passet M, et al. Among authors: kim r. Blood. 2022 Jun 16;139(24):3505-3518. doi: 10.1182/blood.2021014723. Blood. 2022. PMID: 35316324 Free PMC article.
Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia.
Sebert M, Gachet S, Leblanc T, Rousseau A, Bluteau O, Kim R, Ben Abdelali R, Sicre de Fontbrune F, Maillard L, Fedronie C, Murigneux V, Bellenger L, Naouar N, Quentin S, Hernandez L, Vasquez N, Da Costa M, Prata PH, Larcher L, de Tersant M, Duchmann M, Raimbault A, Trimoreau F, Fenneteau O, Cuccuini W, Gachard N, Auger N, Tueur G, Blanluet M, Gazin C, Souyri M, Langa Vives F, Mendez-Bermudez A, Lapillonne H, Lengline E, Raffoux E, Fenaux P, Adès L, Forcade E, Jubert C, Domenech C, Strullu M, Bruno B, Buchbinder N, Thomas C, Petit A, Leverger G, Michel G, Cavazzana M, Gluckman E, Bertrand Y, Boissel N, Baruchel A, Dalle JH, Clappier E, Gilson E, Deriano L, Chevret S, Sigaux F, Socié G, Stoppa-Lyonnet D, de Thé H, Antoniewski C, Bluteau D, Peffault de Latour R, Soulier J. Sebert M, et al. Among authors: kim r. Cell Stem Cell. 2023 Feb 2;30(2):153-170.e9. doi: 10.1016/j.stem.2023.01.006. Cell Stem Cell. 2023. PMID: 36736290 Free article.
Clonal dominance is an adverse prognostic factor in acute myeloid leukemia treated with intensive chemotherapy.
Cerrano M, Duchmann M, Kim R, Vasseur L, Hirsch P, Thomas X, Quentin S, Pasanisi J, Passet M, Rabian F, Rahmé R, Lengliné E, Raffoux E, Dhédin N, Sébert M, Maarek O, Raimbault A, Celli-Lebras K, Adès L, Fenaux P, Boissel N, Delhommeau F, Soulier J, Dombret H, Clappier E, Sujobert P, Itzykson R. Cerrano M, et al. Among authors: kim r. Leukemia. 2021 Mar;35(3):712-723. doi: 10.1038/s41375-020-0932-8. Epub 2020 Jun 24. Leukemia. 2021. PMID: 32581253
4,579 results