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Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse model.
Takwale AD, Kim EY, Jang Y, Lee DH, Kim S, Choi Y, Kim JH, Lee DY, Kim Y, Lee SM, Lee HK, Nam HJ, Lee JY, Cho JH, Moon JH, Lee GS, Kim JH, Kim P, Park CH, Hwang JY. Takwale AD, et al. Among authors: kim ey, kim s, kim p, kim y, kim jh. Bioorg Chem. 2022 Oct;127:105923. doi: 10.1016/j.bioorg.2022.105923. Epub 2022 Jun 13. Bioorg Chem. 2022. PMID: 35717803 Free article.
Discovery of novel tetrahydroisoquinoline-containing pyrimidines as ALK inhibitors.
Achary R, Yun JI, Park CM, Mathi GR, Lee JY, Ha JD, Chae CH, Ahn S, Park CH, Lee CO, Hwang JY, Yun CS, Jung HJ, Cho SY, Kim HR, Kim P. Achary R, et al. Among authors: kim p, kim hr. Bioorg Med Chem. 2016 Jan 15;24(2):207-19. doi: 10.1016/j.bmc.2015.12.004. Epub 2015 Dec 7. Bioorg Med Chem. 2016. PMID: 26712094
A novel cereblon modulator for targeted protein degradation.
Kim SA, Go A, Jo SH, Park SJ, Jeon YU, Kim JE, Lee HK, Park CH, Lee CO, Park SG, Kim P, Park BC, Cho SY, Kim S, Ha JD, Kim JH, Hwang JY. Kim SA, et al. Among authors: kim s, kim p, kim je, kim jh. Eur J Med Chem. 2019 Mar 15;166:65-74. doi: 10.1016/j.ejmech.2019.01.023. Epub 2019 Jan 17. Eur J Med Chem. 2019. PMID: 30684871
Novel bis-ortho-alkoxy-para-piperazinesubstituted-2,4-dianilinopyrimidines (KRCA-0008) as potent and selective ALK inhibitors for anticancer treatment.
Park CH, Choe H, Jang IY, Kwon SY, Latif M, Lee HK, Lee HJ, Yang EH, Yun JI, Chae CH, Cho SY, Choi SU, Ha JD, Jung H, Kim HR, Kim P, Lee CO, Yun CS, Lee K. Park CH, et al. Among authors: kim p, kim hr. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6192-6. doi: 10.1016/j.bmcl.2013.08.090. Epub 2013 Sep 4. Bioorg Med Chem Lett. 2013. PMID: 24095090
4,826 results