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Discovery of a peripheral 5HT2A antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitis.
Pagire HS, Pagire SH, Jeong BK, Choi WI, Oh CJ, Lim CW, Kim M, Yoon J, Kim SS, Bae MA, Jeon JH, Song S, Lee HJ, Lee EY, Goughnour PC, Kim D, Lee IK, Loomba R, Kim H, Ahn JH. Pagire HS, et al. Among authors: kim ss, kim h, kim d, kim m. Nat Commun. 2024 Jan 20;15(1):645. doi: 10.1038/s41467-024-44874-3. Nat Commun. 2024. PMID: 38245505 Free PMC article.
Design, Synthesis, and Biological Evaluation of New Peripheral 5HT2A Antagonists for Nonalcoholic Fatty Liver Disease.
Kim M, Hwang I, Pagire HS, Pagire SH, Choi W, Choi WG, Yoon J, Lee WM, Song JS, Yoo EK, Lee SM, Kim MJ, Bae MA, Kim D, Lee H, Lee EY, Jeon JH, Lee IK, Kim H, Ahn JH. Kim M, et al. Among authors: kim h, kim d, kim mj. J Med Chem. 2020 Apr 23;63(8):4171-4182. doi: 10.1021/acs.jmedchem.0c00002. Epub 2020 Apr 14. J Med Chem. 2020. PMID: 32285676
Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.
Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH. Lee D, et al. Among authors: kim m. J Med Chem. 2019 Jan 24;62(2):575-588. doi: 10.1021/acs.jmedchem.8b01168. Epub 2019 Jan 9. J Med Chem. 2019. PMID: 30623649
Correction to Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.
Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH. Lee D, et al. Among authors: kim m. J Med Chem. 2019 Mar 14;62(5):2849. doi: 10.1021/acs.jmedchem.9b00249. Epub 2019 Feb 27. J Med Chem. 2019. PMID: 30811938 No abstract available.
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