Tet1 overexpression leads to anxiety-like behavior and enhanced fear memories via the activation of calcium-dependent cascade through Egr1 expression in mice.
Kwon W, Kim HS, Jeong J, Sung Y, Choi M, Park S, Lee J, Jang S, Kim SH, Lee S, Kim MO, Ryoo ZY.
Kwon W, et al. Among authors: kim mo, kim sh, kim hs.
FASEB J. 2018 Jan;32(1):390-403. doi: 10.1096/fj.201601340RR. Epub 2017 Sep 12.
FASEB J. 2018.
PMID: 28899881
Taken together, we suggest that the Tet1 overexpression in our Tet1-TG mice can be applied as an effective model for studying various stress-related diseases that show hyperactivation of intracellular calcium-dependent cascades in the brain.-Kwon, W., Kim, H.-S., Jeong, J. …
Taken together, we suggest that the Tet1 overexpression in our Tet1-TG mice can be applied as an effective model for studying various stress …