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Reprogramming competence of OCT factors is determined by transactivation domains.
Kim KP, Wu Y, Yoon J, Adachi K, Wu G, Velychko S, MacCarthy CM, Shin B, Röpke A, Arauzo-Bravo MJ, Stehling M, Han DW, Gao Y, Kim J, Gao S, Schöler HR. Kim KP, et al. Among authors: kim j. Sci Adv. 2020 Sep 2;6(36):eaaz7364. doi: 10.1126/sciadv.aaz7364. Print 2020 Sep. Sci Adv. 2020. PMID: 32917606 Free PMC article.
Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering.
Tan DS, Chen Y, Gao Y, Bednarz A, Wei Y, Malik V, Ho DH, Weng M, Ho SY, Srivastava Y, Velychko S, Yang X, Fan L, Kim J, Graumann J, Stormo GD, Braun T, Yan J, Schöler HR, Jauch R. Tan DS, et al. Among authors: kim j. Mol Biol Evol. 2021 Jun 25;38(7):2854-2868. doi: 10.1093/molbev/msab075. Mol Biol Evol. 2021. PMID: 33720298 Free PMC article.
Donor cell memory confers a metastable state of directly converted cells.
Kim KP, Li C, Bunina D, Jeong HW, Ghelman J, Yoon J, Shin B, Park H, Han DW, Zaugg JB, Kim J, Kuhlmann T, Adams RH, Noh KM, Goldman SA, Schöler HR. Kim KP, et al. Among authors: kim j. Cell Stem Cell. 2021 Jul 1;28(7):1291-1306.e10. doi: 10.1016/j.stem.2021.02.023. Epub 2021 Apr 12. Cell Stem Cell. 2021. PMID: 33848472 Free article.
The homeobox transcription factor DUXBL controls exit from totipotency.
Vega-Sendino M, Lüttmann FF, Olbrich T, Chen Y, Kuenne C, Stein P, Tillo D, Carey GI, Zhong J, Savy V, Radonova L, Lu T, Saykali B, Kim KP, Domingo CN, Schüler L, Günther S, Bentsen M, Bosnakovski D, Schöler H, Kyba M, Maity TK, Jenkins LM, Looso M, Williams CJ, Kim J, Ruiz S. Vega-Sendino M, et al. Among authors: kim kp, kim j. Nat Genet. 2024 Apr;56(4):697-709. doi: 10.1038/s41588-024-01692-z. Epub 2024 Mar 20. Nat Genet. 2024. PMID: 38509386
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