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Sirt3, mitochondrial ROS, ageing, and carcinogenesis.
Park SH, Ozden O, Jiang H, Cha YI, Pennington JD, Aykin-Burns N, Spitz DR, Gius D, Kim HS. Park SH, et al. Among authors: kim hs. Int J Mol Sci. 2011;12(9):6226-39. doi: 10.3390/ijms12096226. Epub 2011 Sep 23. Int J Mol Sci. 2011. PMID: 22016654 Free PMC article. Review.
SIRT2 directs the replication stress response through CDK9 deacetylation.
Zhang H, Park SH, Pantazides BG, Karpiuk O, Warren MD, Hardy CW, Duong DM, Park SJ, Kim HS, Vassilopoulos A, Seyfried NT, Johnsen SA, Gius D, Yu DS. Zhang H, et al. Among authors: kim hs. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13546-51. doi: 10.1073/pnas.1301463110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898190 Free PMC article.
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress.
Kim HS, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, Pennington JD, van der Meer R, Nguyen P, Savage J, Owens KM, Vassilopoulos A, Ozden O, Park SH, Singh KK, Abdulkadir SA, Spitz DR, Deng CX, Gius D. Kim HS, et al. Cancer Cell. 2010 Jan 19;17(1):41-52. doi: 10.1016/j.ccr.2009.11.023. Cancer Cell. 2010. PMID: 20129246 Free PMC article.
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