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SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice.
El Chehadeh S, Han KA, Kim D, Jang G, Bakhtiari S, Lim D, Kim HY, Kim J, Kim H, Wynn J, Chung WK, Vitiello G, Cutcutache I, Page M, Gecz J, Harper K, Han AR, Kim HM, Wessels M, Bayat A, Jaén AF, Selicorni A, Maitz S, de Brouwer APM, Silfhout AV, Armstrong M, Symonds J, Küry S, Isidor B, Cogné B, Nizon M, Feger C, Muller J, Torti E, Grange DK, Willems M, Kruer MC, Ko J, Piton A, Um JW. El Chehadeh S, et al. Among authors: kim hy, kim h, kim d, kim hm, kim j. Nat Commun. 2022 Jul 15;13(1):4112. doi: 10.1038/s41467-022-31566-z. Nat Commun. 2022. PMID: 35840571 Free PMC article.
Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.
Um JW, Kim KH, Park BS, Choi Y, Kim D, Kim CY, Kim SJ, Kim M, Ko JS, Lee SG, Choii G, Nam J, Heo WD, Kim E, Lee JO, Ko J, Kim HM. Um JW, et al. Among authors: kim e, kim d, kim hm, kim cy, kim sj, kim m, kim kh. Nat Commun. 2014 Nov 14;5:5423. doi: 10.1038/ncomms6423. Nat Commun. 2014. PMID: 25394468 Free article.
PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.
Ko JS, Pramanik G, Um JW, Shim JS, Lee D, Kim KH, Chung GY, Condomitti G, Kim HM, Kim H, de Wit J, Park KS, Tabuchi K, Ko J. Ko JS, et al. Among authors: kim h, kim hm, kim kh. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1874-9. doi: 10.1073/pnas.1410138112. Epub 2015 Jan 26. Proc Natl Acad Sci U S A. 2015. PMID: 25624497 Free PMC article.
Designed nucleases for targeted genome editing.
Lee J, Chung JH, Kim HM, Kim DW, Kim H. Lee J, et al. Among authors: kim h, kim dw, kim hm. Plant Biotechnol J. 2016 Feb;14(2):448-62. doi: 10.1111/pbi.12465. Epub 2015 Sep 15. Plant Biotechnol J. 2016. PMID: 26369767 Free article. Review.
3,229 results