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(5-Hydroxy-4-oxo-4H-pyran-2-yl)methyl 6-hydroxynaphthalene-2-carboxylate, a kojic acid derivative, inhibits inflammatory mediator production via the suppression of Syk/Src and NF-κB activation.
Dung TT, Kim SC, Yoo BC, Sung GH, Yang WS, Kim HG, Park JG, Rhee MH, Park KW, Yoon K, Lee Y, Hong S, Kim JH, Cho JY. Dung TT, et al. Int Immunopharmacol. 2014 May;20(1):37-45. doi: 10.1016/j.intimp.2014.02.019. Epub 2014 Feb 26. Int Immunopharmacol. 2014. PMID: 24583147
PDK1 disruptors and modulators: a patent review.
Hossen MJ, Kim SC, Yang S, Kim HG, Jeong D, Yi YS, Sung NY, Lee JO, Kim JH, Cho JY. Hossen MJ, et al. Expert Opin Ther Pat. 2015 May;25(5):513-37. doi: 10.1517/13543776.2015.1014801. Epub 2015 Feb 15. Expert Opin Ther Pat. 2015. PMID: 25684022 Review.
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