SUV39H1/DNMT3A-dependent methylation of the RB1 promoter stimulates PIN1 expression and melanoma development.
Kim G, Kim JY, Lim SC, Lee KY, Kim O, Choi HS.
Kim G, et al. Among authors: kim jy, kim o.
FASEB J. 2018 Oct;32(10):5647-5660. doi: 10.1096/fj.201700645RRRRR. Epub 2018 May 11.
FASEB J. 2018.
PMID: 29750576
Our studies establish SUV39H1 as an oncogene in melanoma and underscore the role of chromatin factors in regulating tumorigenesis.-Kim, G., Kim, J.-Y., Lim, S.-C., Lee, K. Y., Kim, O., Choi, H. S. ...
Our studies establish SUV39H1 as an oncogene in melanoma and underscore the role of chromatin factors in regulating tumorigenesis.-Kim …