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Loop-extruding Smc5/6 organizes transcription-induced positive DNA supercoils.
Jeppsson K, Pradhan B, Sutani T, Sakata T, Umeda Igarashi M, Berta DG, Kanno T, Nakato R, Shirahige K, Kim E, Björkegren C. Jeppsson K, et al. Among authors: kim e. Mol Cell. 2024 Mar 7;84(5):867-882.e5. doi: 10.1016/j.molcel.2024.01.005. Epub 2024 Jan 30. Mol Cell. 2024. PMID: 38295804 Free article.
Condensin-driven loop extrusion on supercoiled DNA.
Kim E, Gonzalez AM, Pradhan B, van der Torre J, Dekker C. Kim E, et al. Nat Struct Mol Biol. 2022 Jul;29(7):719-727. doi: 10.1038/s41594-022-00802-x. Epub 2022 Jul 14. Nat Struct Mol Biol. 2022. PMID: 35835864
SMC complexes can traverse physical roadblocks bigger than their ring size.
Pradhan B, Barth R, Kim E, Davidson IF, Bauer B, van Laar T, Yang W, Ryu JK, van der Torre J, Peters JM, Dekker C. Pradhan B, et al. Among authors: kim e. Cell Rep. 2022 Oct 18;41(3):111491. doi: 10.1016/j.celrep.2022.111491. Cell Rep. 2022. PMID: 36261017 Free article.
The Smc5/6 complex is a DNA loop-extruding motor.
Pradhan B, Kanno T, Umeda Igarashi M, Loke MS, Baaske MD, Wong JSK, Jeppsson K, Björkegren C, Kim E. Pradhan B, et al. Among authors: kim e. Nature. 2023 Apr;616(7958):843-848. doi: 10.1038/s41586-023-05963-3. Epub 2023 Apr 19. Nature. 2023. PMID: 37076626 Free PMC article.
Distinct Roles for Condensin's Two ATPase Sites in Chromosome Condensation.
Elbatsh AMO, Kim E, Eeftens JM, Raaijmakers JA, van der Weide RH, García-Nieto A, Bravo S, Ganji M, Uit de Bos J, Teunissen H, Medema RH, de Wit E, Haering CH, Dekker C, Rowland BD. Elbatsh AMO, et al. Among authors: kim e. Mol Cell. 2019 Dec 5;76(5):724-737.e5. doi: 10.1016/j.molcel.2019.09.020. Epub 2019 Oct 16. Mol Cell. 2019. PMID: 31629658 Free PMC article.
Real-time imaging of DNA loop extrusion by condensin.
Ganji M, Shaltiel IA, Bisht S, Kim E, Kalichava A, Haering CH, Dekker C. Ganji M, et al. Among authors: kim e. Science. 2018 Apr 6;360(6384):102-105. doi: 10.1126/science.aar7831. Epub 2018 Feb 22. Science. 2018. PMID: 29472443 Free PMC article.
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