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Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype.
Valdés-Mora F, Salomon R, Gloss BS, Law AMK, Venhuizen J, Castillo L, Murphy KJ, Magenau A, Papanicolaou M, Rodriguez de la Fuente L, Roden DL, Colino-Sanguino Y, Kikhtyak Z, Farbehi N, Conway JRW, Sikta N, Oakes SR, Cox TR, O'Donoghue SI, Timpson P, Ormandy CJ, Gallego-Ortega D. Valdés-Mora F, et al. Among authors: kikhtyak z. Cell Rep. 2021 Apr 13;35(2):108945. doi: 10.1016/j.celrep.2021.108945. Cell Rep. 2021. PMID: 33852842 Free article.
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.
Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhtyak Z, Cho C, Allerdice SL, Lee HJ, Valdes-Mora F, Herrmann D, Salomon R, Young AI, Lee BY, Sergio CM, Kaplan W, Piggin C, Conway JR, Rabinovich B, Millar EK, Oakes SR, Chtanova T, Swarbrick A, Naylor MJ, O'Toole S, Green AR, Timpson P, Gee JM, Ellis IO, Clark SJ, Ormandy CJ. Gallego-Ortega D, et al. Among authors: kikhtyak z. PLoS Biol. 2015 Dec 30;13(12):e1002330. doi: 10.1371/journal.pbio.1002330. eCollection 2015 Dec. PLoS Biol. 2015. PMID: 26717410 Free PMC article.
A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.
Oakes SR, Gallego-Ortega D, Stanford PM, Junankar S, Au WWY, Kikhtyak Z, von Korff A, Sergio CM, Law AMK, Castillo LE, Allerdice SL, Young AIJ, Piggin C, Whittle B, Bertram E, Naylor MJ, Roden DL, Donovan J, Korennykh A, Goodnow CC, O'Bryan MK, Ormandy CJ. Oakes SR, et al. Among authors: kikhtyak z. PLoS Genet. 2017 Nov 8;13(11):e1007072. doi: 10.1371/journal.pgen.1007072. eCollection 2017 Nov. PLoS Genet. 2017. PMID: 29117179 Free PMC article.
Selective inhibition of CDK9 in triple negative breast cancer.
Mustafa EH, Laven-Law G, Kikhtyak Z, Nguyen V, Ali S, Pace AA, Iggo R, Kebede A, Noll B, Wang S, Winter JM, Dwyer AR, Tilley WD, Hickey TE. Mustafa EH, et al. Among authors: kikhtyak z. Oncogene. 2024 Jan;43(3):202-215. doi: 10.1038/s41388-023-02892-3. Epub 2023 Nov 24. Oncogene. 2024. PMID: 38001268 Free PMC article.
A cell permeable bimane-constrained PCNA-interacting peptide.
Horsfall AJ, Vandborg BA, Kikhtyak Z, Scanlon DB, Tilley WD, Hickey TE, Bruning JB, Abell AD. Horsfall AJ, et al. Among authors: kikhtyak z. RSC Chem Biol. 2021 Jul 21;2(5):1499-1508. doi: 10.1039/d1cb00113b. eCollection 2021 Oct 7. RSC Chem Biol. 2021. PMID: 34704055 Free PMC article.