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The treatment with sGC stimulator improves survival of hypertensive rats in response to volume-overload induced by aorto-caval fistula.
Gawrys O, Husková Z, Škaroupková P, Honetschlägerová Z, Vaňourková Z, Kikerlová S, Melenovský V, Bačová BS, Sykora M, Táborský M, Červenka L. Gawrys O, et al. Among authors: kikerlova s. Naunyn Schmiedebergs Arch Pharmacol. 2023 Dec;396(12):3757-3773. doi: 10.1007/s00210-023-02561-y. Epub 2023 Jun 20. Naunyn Schmiedebergs Arch Pharmacol. 2023. PMID: 37338578 Free PMC article.
Renin-angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats.
Sedláková L, Čertíková Chábová V, Doleželová Š, Škaroupková P, Kopkan L, Husková Z, Červenková L, Kikerlová S, Vaněčková I, Sadowski J, Kompanowska-Jezierska E, Kujal P, Kramer HJ, Červenka L. Sedláková L, et al. Among authors: kikerlova s. Clin Exp Hypertens. 2017;39(2):183-195. doi: 10.1080/10641963.2016.1235184. Epub 2017 Mar 1. Clin Exp Hypertens. 2017. PMID: 28287881
Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease.
Čertíková Chábová V, Kujal P, Škaroupková P, Varňourková Z, Vacková Š, Husková Z, Kikerlová S, Sadowski J, Kompanowska-Jezierska E, Baranowska I, Hwang SH, Hammock BD, Imig JD, Tesař V, Červenka L. Čertíková Chábová V, et al. Among authors: kikerlova s. Kidney Blood Press Res. 2018;43(2):329-349. doi: 10.1159/000487902. Epub 2018 Mar 6. Kidney Blood Press Res. 2018. PMID: 29529602 Free PMC article.
Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.
Červenka L, Husková Z, Kopkan L, Kikerlová S, Sedláková L, Vaňourková Z, Alánová P, Kolář F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neckář J. Červenka L, et al. Among authors: kikerlova s. J Hypertens. 2018 Jun;36(6):1326-1341. doi: 10.1097/HJH.0000000000001708. J Hypertens. 2018. PMID: 29570510 Free PMC article.
20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Sedláková L, Kikerlová S, Husková Z, Červenková L, Chábová VČ, Zicha J, Falck JR, Imig JD, Kompanowska-Jezierska E, Sadowski J, Krátký V, Červenka L, Kopkan L. Sedláková L, et al. Among authors: kikerlova s. Biosci Rep. 2018 Sep 12;38(5):BSR20171496. doi: 10.1042/BSR20171496. Print 2018 Oct 31. Biosci Rep. 2018. PMID: 30054426 Free PMC article.
Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats.
Vacková Š, Kopkan L, Kikerlová S, Husková Z, Sadowski J, Kompanowska-Jezierska E, Hammock BD, Imig JD, Táborský M, Melenovský V, Červenka L. Vacková Š, et al. Among authors: kikerlova s. Front Pharmacol. 2019 Jan 23;10:18. doi: 10.3389/fphar.2019.00018. eCollection 2019. Front Pharmacol. 2019. PMID: 30728778 Free PMC article.
Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats.
Hrdlička J, Neckář J, Papoušek F, Husková Z, Kikerlová S, Vaňourková Z, Vernerová Z, Akat F, Vašinová J, Hammock BD, Hwang SH, Imig JD, Falck JR, Červenka L, Kolář F. Hrdlička J, et al. Among authors: kikerlova s. Front Pharmacol. 2019 Mar 1;10:159. doi: 10.3389/fphar.2019.00159. eCollection 2019. Front Pharmacol. 2019. PMID: 30881303 Free PMC article.
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