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Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion.
Hong SM, Jung D, Kiemen A, Gaida MM, Yoshizawa T, Braxton AM, Noë M, Lionheart G, Oshima K, Thompson ED, Burkhart R, Wu PH, Wirtz D, Hruban RH, Wood LD. Hong SM, et al. Mod Pathol. 2020 Apr;33(4):639-647. doi: 10.1038/s41379-019-0409-3. Epub 2019 Nov 7. Mod Pathol. 2020. PMID: 31700162 Free PMC article.
Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth.
Xue Y, Lyu C, Taylor A, Van Ee A, Kiemen A, Choi Y, Khavanian N, Henn D, Lee C, Hwang L, Wier E, Wang S, Lee S, Li A, Kirby C, Wang G, Wu PH, Wirtz D, Garza LA, Reddy SK. Xue Y, et al. Sci Adv. 2022 Apr 29;8(17):eabl8698. doi: 10.1126/sciadv.abl8698. Epub 2022 Apr 27. Sci Adv. 2022. PMID: 35476447 Free PMC article.
Deep learning identification of stiffness markers in breast cancer.
Sneider A, Kiemen A, Kim JH, Wu PH, Habibi M, White M, Phillip JM, Gu L, Wirtz D. Sneider A, et al. Biomaterials. 2022 Jun;285:121540. doi: 10.1016/j.biomaterials.2022.121540. Epub 2022 Apr 27. Biomaterials. 2022. PMID: 35537336 Free PMC article.
CODA: quantitative 3D reconstruction of large tissues at cellular resolution.
Kiemen AL, Braxton AM, Grahn MP, Han KS, Babu JM, Reichel R, Jiang AC, Kim B, Hsu J, Amoa F, Reddy S, Hong SM, Cornish TC, Thompson ED, Huang P, Wood LD, Hruban RH, Wirtz D, Wu PH. Kiemen AL, et al. Nat Methods. 2022 Nov;19(11):1490-1499. doi: 10.1038/s41592-022-01650-9. Epub 2022 Oct 24. Nat Methods. 2022. PMID: 36280719 Free PMC article.
Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer.
Kiemen AL, Choi Y, Braxton AM, Almagro Pérez C, Graham S, Grahn MP, Nanda N, Roberts N, Wood L, Wu P, Hruban RH, Wirtz D. Kiemen AL, et al. Histopathology. 2023 Feb;82(3):504-506. doi: 10.1111/his.14839. Epub 2022 Nov 21. Histopathology. 2023. PMID: 36371607 Free PMC article.
Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscopic focus of pancreatic cancer found in the vasculature of grossly normal human pancreas tissue resected adjacent to a large tumour. ...
Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscop …
26 results