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Efficient ex vivo expansion of conserved element vaccine-specific CD8+ T-cells from SHIV-infected, ART-suppressed nonhuman primates.
Dross S, Venkataraman R, Patel S, Huang ML, Bollard CM, Rosati M, Pavlakis GN, Felber BK, Bar KJ, Shaw GM, Jerome KR, Mullins JI, Kiem HP, Fuller DH, Peterson CW. Dross S, et al. Among authors: kiem hp. Front Immunol. 2023 May 3;14:1188018. doi: 10.3389/fimmu.2023.1188018. eCollection 2023. Front Immunol. 2023. PMID: 37207227 Free PMC article.
Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers.
Eichholz K, Fukazawa Y, Peterson CW, Haeseleer F, Medina M, Hoffmeister S, Duell DM, Varco-Merth BD, Dross S, Park H, Labriola CS, Axthelm MK, Murnane RD, Smedley JV, Jin L, Gong J, Rust BJ, Fuller DH, Kiem HP, Picker LJ, Okoye AA, Corey L. Eichholz K, et al. Among authors: kiem hp. J Clin Invest. 2024 Apr 1;134(7):e169309. doi: 10.1172/JCI169309. J Clin Invest. 2024. PMID: 38557496 Free PMC article.
Extending Gene Medicines to All in Need.
McCune JM, Kiem HP. McCune JM, et al. Among authors: kiem hp. N Engl J Med. 2024 May 9;390(18):1721-1722. doi: 10.1056/NEJMe2403104. Epub 2024 Apr 24. N Engl J Med. 2024. PMID: 38657269 No abstract available.
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice.
Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide C, Tolar J, Panoskaltsis-Mortari A, Gorfinkel L, Tkachev V, Gerdemann U, Alvarez-Calderon F, Palato ER, MacMillan ML, Wagner JE, Kean LS, Osborn M, Kiem HP, Scadden DT, Olson LM, Blazar BR. Saha A, et al. Among authors: kiem hp. Blood. 2024 Mar 6:blood.2023023549. doi: 10.1182/blood.2023023549. Online ahead of print. Blood. 2024. PMID: 38447038
Answering the "Doctor, can CAR-T therapy cause cancer?" question in clinic.
Banerjee R, Poh C, Hirayama AV, Gauthier J, Cassaday RD, Shadman M, Cowan AJ, Till BG, Green DJ, Kiem HP, Gopal AK, Maloney DG. Banerjee R, et al. Among authors: kiem hp. Blood Adv. 2024 Feb 27;8(4):895-898. doi: 10.1182/bloodadvances.2023012336. Blood Adv. 2024. PMID: 38197942 Free PMC article. No abstract available.
345 results