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Improving CNS Delivery to Brain Metastases by Blood-Tumor Barrier Disruption.
Trends Cancer. 2019 Aug;5(8):495-505. doi: 10.1016/j.trecan.2019.06.003. Epub 2019 Jul 20.
Trends Cancer. 2019.
PMID: 31421906
Free PMC article.
Review.
Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery.
Arsiwala TA, Sprowls SA, Blethen KE, Adkins CE, Saralkar PA, Fladeland RA, Pentz W, Gabriele A, Kielkowski B, Mehta RI, Wang P, Carpenter JS, Ranjan M, Najib U, Rezai AR, Lockman PR.
Arsiwala TA, et al.
Neoplasia. 2021 Jul;23(7):676-691. doi: 10.1016/j.neo.2021.04.005. Epub 2021 Jun 14.
Neoplasia. 2021.
PMID: 34139452
Free PMC article.
Review.
Item in Clipboard
Modulation of the blood-tumor barrier to enhance drug delivery and efficacy for brain metastases.
Blethen KE, Arsiwala TA, Fladeland RA, Sprowls SA, Panchal DM, Adkins CE, Kielkowski BN, Earp LE, Glass MJ, Pritt TA, Cabuyao YM, Aulakh S, Lockman PR.
Blethen KE, et al. Among authors: kielkowski bn.
Neurooncol Adv. 2021 Nov 27;3(Suppl 5):v133-v143. doi: 10.1093/noajnl/vdab123. eCollection 2021 Nov.
Neurooncol Adv. 2021.
PMID: 34859240
Free PMC article.
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Characterization of passive permeability after low intensity focused ultrasound mediated blood-brain barrier disruption in a preclinical model.
Arsiwala TA, Sprowls SA, Blethen KE, Fladeland RA, Wolford CP, Kielkowski BN, Glass MJ, Wang P, Wilson O, Carpenter JS, Ranjan M, Finomore V, Rezai A, Lockman PR.
Arsiwala TA, et al. Among authors: kielkowski bn.
Fluids Barriers CNS. 2022 Sep 8;19(1):72. doi: 10.1186/s12987-022-00369-1.
Fluids Barriers CNS. 2022.
PMID: 36076213
Free PMC article.
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Coordination of anti-CTLA-4 with whole-brain radiation therapy decreases tumor burden during treatment in a novel syngeneic model of lung cancer brain metastasis.
Blethen KE, Wolford CP, Pecar GL, Arsiwala TA, Adjeroh E, Dykstra LP, Kielkowski BN, Lockman PR.
Blethen KE, et al. Among authors: kielkowski bn.
Cancer Immunol Immunother. 2024 Jan 19;73(1):20. doi: 10.1007/s00262-023-03599-w.
Cancer Immunol Immunother. 2024.
PMID: 38240876
Free PMC article.
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Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy.
Arsiwala TA, Blethen KE, Wolford CP, Panchal DM, Sprowls SA, Fladeland RA, Kielkowski BN, Pritt TA, Wang P, Wilson O, Carpenter JS, Finomore V, Rezai A, Lockman PR.
Arsiwala TA, et al. Among authors: kielkowski bn.
Front Oncol. 2023 Feb 10;13:1104594. doi: 10.3389/fonc.2023.1104594. eCollection 2023.
Front Oncol. 2023.
PMID: 36845739
Free PMC article.
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Effects of whole-brain radiation therapy on the blood-brain barrier in immunocompetent and immunocompromised mouse models.
Blethen KE, Sprowls SA, Arsiwala TA, Wolford CP, Panchal DM, Fladeland RA, Glass MJ, Dykstra LP, Kielkowski BN, Blackburn JR, Andrick CJ, Lockman PR.
Blethen KE, et al. Among authors: kielkowski bn.
Radiat Oncol. 2023 Feb 3;18(1):22. doi: 10.1186/s13014-023-02215-6.
Radiat Oncol. 2023.
PMID: 36732754
Free PMC article.
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