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TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality.
Persyn E, Wahlen S, Kiekens L, Taveirne S, Van Loocke W, Van Ammel E, Van Nieuwerburgh F, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Persyn E, et al. Among authors: kiekens l. Int J Mol Sci. 2022 Sep 26;23(19):11345. doi: 10.3390/ijms231911345. Int J Mol Sci. 2022. PMID: 36232644 Free PMC article.
The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation.
Taveirne S, Wahlen S, Van Loocke W, Kiekens L, Persyn E, Van Ammel E, De Mulder K, Roels J, Tilleman L, Aumercier M, Matthys P, Van Nieuwerburgh F, Kerre TCC, Taghon T, Van Vlierberghe P, Vandekerckhove B, Leclercq G. Taveirne S, et al. Among authors: kiekens l. Blood. 2020 Jul 16;136(3):288-298. doi: 10.1182/blood.2020005204. Blood. 2020. PMID: 32350509 Free article.
IRF2 is required for development and functional maturation of human NK cells.
Persyn E, Wahlen S, Kiekens L, Van Loocke W, Siwe H, Van Ammel E, De Vos Z, Van Nieuwerburgh F, Matthys P, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Persyn E, et al. Among authors: kiekens l. Front Immunol. 2022 Dec 5;13:1038821. doi: 10.3389/fimmu.2022.1038821. eCollection 2022. Front Immunol. 2022. PMID: 36544762 Free PMC article.