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TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models.
Dominguez SL, Laufer BI, Ghosh AS, Li Q, Ruggeri G, Emani MR, Phu L, Friedman BA, Sandoval W, Rose CM, Ngu H, Foreman O, Reichelt M, Juste Y, Lalehzadeh G, Hansen D, Nymark H, Mellal D, Gylling H, Kiełpiński ŁJ, Chih B, Bingol B, Hoogenraad CC, Meilandt WJ, Easton A. Dominguez SL, et al. Among authors: kielpinski lj. iScience. 2023 Oct 29;26(11):108362. doi: 10.1016/j.isci.2023.108362. eCollection 2023 Nov 17. iScience. 2023. PMID: 37965143 Free PMC article.
Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers.
Duschmalé J, Schäublin A, Funder E, Schmidt S, Kiełpiński ŁJ, Nymark H, Jensen K, Koch T, Duschmalé M, Koller E, Møller MR, Schadt S, Husser C, Brink A, Sewing S, Minz T, Wengel J, Bleicher K, Li M. Duschmalé J, et al. Among authors: kielpinski lj. Mol Ther Nucleic Acids. 2022 Jun 22;29:176-188. doi: 10.1016/j.omtn.2022.06.010. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 35860384 Free PMC article.
AntimiR targeting of microRNA-134 reduces seizures in a mouse model of Angelman syndrome.
Campbell A, Morris G, Sanfeliu A, Augusto J, Langa E, Kesavan JC, Nguyen NT, Conroy RM, Worm J, Kielpinski L, Jensen MA, Miller MT, Kremer T, Reschke CR, Henshall DC. Campbell A, et al. Mol Ther Nucleic Acids. 2022 Apr 20;28:514-529. doi: 10.1016/j.omtn.2022.04.009. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35592499 Free PMC article.
11 results