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Page 1
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis.
Edgar L, Akbar N, Braithwaite AT, Krausgruber T, Gallart-Ayala H, Bailey J, Corbin AL, Khoyratty TE, Chai JT, Alkhalil M, Rendeiro AF, Ziberna K, Arya R, Cahill TJ, Bock C, Laurencikiene J, Crabtree MJ, Lemieux ME, Riksen NP, Netea MG, Wheelock CE, Channon KM, Rydén M, Udalova IA, Carnicer R, Choudhury RP. Edgar L, et al. Among authors: khoyratty te. Circulation. 2021 Sep 21;144(12):961-982. doi: 10.1161/CIRCULATIONAHA.120.046464. Epub 2021 Jul 13. Circulation. 2021. PMID: 34255973 Free PMC article.
Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.
Seneviratne AN, Edsfeldt A, Cole JE, Kassiteridi C, Swart M, Park I, Green P, Khoyratty T, Saliba D, Goddard ME, Sansom SN, Goncalves I, Krams R, Udalova IA, Monaco C. Seneviratne AN, et al. Circulation. 2017 Sep 19;136(12):1140-1154. doi: 10.1161/CIRCULATIONAHA.117.027844. Epub 2017 Jul 11. Circulation. 2017. PMID: 28698173 Free PMC article.
Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
Ryzhakov G, Almuttaqi H, Corbin AL, Berthold DL, Khoyratty T, Eames HL, Bullers S, Pearson C, Ai Z, Zec K, Bonham S, Fischer R, Jostins-Dean L, Travis SPL, Kessler BM, Udalova IA. Ryzhakov G, et al. Nat Commun. 2021 Nov 18;12(1):6702. doi: 10.1038/s41467-021-27038-5. Nat Commun. 2021. PMID: 34795257 Free PMC article.
IRF5 regulates airway macrophage metabolic responses.
Albers GJ, Iwasaki J, McErlean P, Ogger PP, Ghai P, Khoyratty TE, Udalova IA, Lloyd CM, Byrne AJ. Albers GJ, et al. Among authors: khoyratty te. Clin Exp Immunol. 2021 Apr;204(1):134-143. doi: 10.1111/cei.13573. Epub 2021 Jan 28. Clin Exp Immunol. 2021. PMID: 33423291 Free PMC article.
Distinct transcription factor networks control neutrophil-driven inflammation.
Khoyratty TE, Ai Z, Ballesteros I, Eames HL, Mathie S, Martín-Salamanca S, Wang L, Hemmings A, Willemsen N, von Werz V, Zehrer A, Walzog B, van Grinsven E, Hidalgo A, Udalova IA. Khoyratty TE, et al. Nat Immunol. 2021 Sep;22(9):1093-1106. doi: 10.1038/s41590-021-00968-4. Epub 2021 Jul 19. Nat Immunol. 2021. PMID: 34282331 Free PMC article.
Antibody response to homologous epitopes of Epstein-Barr virus, Mycobacterium avium subsp. paratuberculosis and IRF5 in patients with different connective tissue diseases and in mouse model of antigen-induced arthritis.
Bo M, Niegowska M, Eames HL, Almuttaqi H, Arru G, Erre GL, Passiu G, Khoyratty TE, van Grinsven E, Udalova IA, Sechi LA. Bo M, et al. Among authors: khoyratty te. J Transl Autoimmun. 2020 Mar 17;3:100048. doi: 10.1016/j.jtauto.2020.100048. eCollection 2020. J Transl Autoimmun. 2020. PMID: 32743529 Free PMC article.
Co-option of Neutrophil Fates by Tissue Environments.
Ballesteros I, Rubio-Ponce A, Genua M, Lusito E, Kwok I, Fernández-Calvo G, Khoyratty TE, van Grinsven E, González-Hernández S, Nicolás-Ávila JÁ, Vicanolo T, Maccataio A, Benguría A, Li JL, Adrover JM, Aroca-Crevillen A, Quintana JA, Martín-Salamanca S, Mayo F, Ascher S, Barbiera G, Soehnlein O, Gunzer M, Ginhoux F, Sánchez-Cabo F, Nistal-Villán E, Schulz C, Dopazo A, Reinhardt C, Udalova IA, Ng LG, Ostuni R, Hidalgo A. Ballesteros I, et al. Among authors: khoyratty te. Cell. 2020 Nov 25;183(5):1282-1297.e18. doi: 10.1016/j.cell.2020.10.003. Epub 2020 Oct 23. Cell. 2020. PMID: 33098771 Free article.