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The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
Ho P, Melms JC, Rogava M, Frangieh CJ, Poźniak J, Shah SB, Walsh Z, Kyrysyuk O, Amin AD, Caprio L, Fullerton BT, Soni RK, Ager CR, Biermann J, Wang Y, Khosravi-Maharlooei M, Zanetti G, Mu M, Fatima H, Moore EK, Vasan N, Bakhoum SF, Reiner SL, Bernatchez C, Sykes M, Mace EM, Wucherpfennig KW, Schadendorf D, Bechter O, Shah P, Schwartz GK, Marine JC, Izar B. Ho P, et al. Among authors: khosravi maharlooei m. Cancer Cell. 2023 Jul 10;41(7):1207-1221.e12. doi: 10.1016/j.ccell.2023.05.014. Epub 2023 Jun 15. Cancer Cell. 2023. PMID: 37327789
Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators.
Obradovic A, Ager C, Turunen M, Nirschl T, Khosravi-Maharlooei M, Iuga A, Jackson CM, Yegnasubramanian S, Tomassoni L, Fernandez EC, McCann P, Rogava M, DeMarzo AM, Kochel CM, Allaf M, Bivalacqua T, Lim M, Realubit R, Karan C, Drake CG, Califano A. Obradovic A, et al. Among authors: khosravi maharlooei m. Cancer Cell. 2023 May 8;41(5):933-949.e11. doi: 10.1016/j.ccell.2023.04.003. Epub 2023 Apr 27. Cancer Cell. 2023. PMID: 37116491 Free PMC article.
Shifting gears with CAR T cells for autoimmune diseases.
Kale B, Khosravi-Maharlooei M, Perna F. Kale B, et al. Among authors: khosravi maharlooei m. Mol Ther. 2024 Feb 7;32(2):261-263. doi: 10.1016/j.ymthe.2024.01.014. Epub 2024 Jan 20. Mol Ther. 2024. PMID: 38244538 No abstract available.
Modeling human T1D-associated autoimmune processes.
Khosravi-Maharlooei M, Madley R, Borsotti C, Ferreira LMR, Sharp RC, Brehm MA, Greiner DL, Parent AV, Anderson MS, Sykes M, Creusot RJ. Khosravi-Maharlooei M, et al. Mol Metab. 2022 Feb;56:101417. doi: 10.1016/j.molmet.2021.101417. Epub 2021 Dec 10. Mol Metab. 2022. PMID: 34902607 Free PMC article. Review.
Role of the thymus in spontaneous development of a multi-organ autoimmune disease in human immune system mice.
Khosravi-Maharlooei M, Li H, Hoelzl M, Zhao G, Ruiz A, Misra A, Li Y, Teteloshvili N, Nauman G, Danzl N, Ding X, Pinker EY, Obradovic A, Yang YG, Iuga A, Creusot RJ, Winchester R, Sykes M. Khosravi-Maharlooei M, et al. J Autoimmun. 2021 May;119:102612. doi: 10.1016/j.jaut.2021.102612. Epub 2021 Feb 19. J Autoimmun. 2021. PMID: 33611150 Free PMC article.
T cell repertoire analysis suggests a prominent bystander response in human cardiac allograft vasculopathy.
Habal MV, Miller AMI, Rao S, Lin S, Obradovic A, Khosravi-Maharlooei M, See SB, Roy P, Shihab R, Ho SH, Marboe CC, Naka Y, Takeda K, Restaino S, Han A, Mancini D, Givertz M, Madsen JC, Sykes M, Addonizio LJ, Farr MA, Zorn E. Habal MV, et al. Among authors: khosravi maharlooei m. Am J Transplant. 2021 Apr;21(4):1465-1476. doi: 10.1111/ajt.16333. Epub 2020 Oct 26. Am J Transplant. 2021. PMID: 33021057 Free PMC article.
33 results