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Crystal structures of human ENPP1 in apo and bound forms.
Dennis ML, Newman J, Dolezal O, Hattarki M, Surjadi RN, Nuttall SD, Pham T, Nebl T, Camerino M, Khoo PS, Monahan BJ, Peat TS. Dennis ML, et al. Among authors: khoo ps. Acta Crystallogr D Struct Biol. 2020 Sep 1;76(Pt 9):889-898. doi: 10.1107/S2059798320010505. Epub 2020 Aug 17. Acta Crystallogr D Struct Biol. 2020. PMID: 32876064 Free PMC article.
HBO1 is required for the maintenance of leukaemia stem cells.
MacPherson L, Anokye J, Yeung MM, Lam EYN, Chan YC, Weng CF, Yeh P, Knezevic K, Butler MS, Hoegl A, Chan KL, Burr ML, Gearing LJ, Willson T, Liu J, Choi J, Yang Y, Bilardi RA, Falk H, Nguyen N, Stupple PA, Peat TS, Zhang M, de Silva M, Carrasco-Pozo C, Avery VM, Khoo PS, Dolezal O, Dennis ML, Nuttall S, Surjadi R, Newman J, Ren B, Leaver DJ, Sun Y, Baell JB, Dovey O, Vassiliou GS, Grebien F, Dawson SJ, Street IP, Monahan BJ, Burns CJ, Choudhary C, Blewitt ME, Voss AK, Thomas T, Dawson MA. MacPherson L, et al. Among authors: khoo ps. Nature. 2020 Jan;577(7789):266-270. doi: 10.1038/s41586-019-1835-6. Epub 2019 Dec 11. Nature. 2020. PMID: 31827282
Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity.
Chaudhuri R, Khoo PS, Tonks K, Junutula JR, Kolumam G, Modrusan Z, Samocha-Bonet D, Meoli CC, Hocking S, Fazakerley DJ, Stöckli J, Hoehn KL, Greenfield JR, Yang JYH, James DE. Chaudhuri R, et al. Among authors: khoo ps. NPJ Syst Biol Appl. 2015 Nov 12;1:15010. doi: 10.1038/npjsba.2015.10. eCollection 2015. NPJ Syst Biol Appl. 2015. PMID: 28725461 Free PMC article.
Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway.
Trefely S, Khoo PS, Krycer JR, Chaudhuri R, Fazakerley DJ, Parker BL, Sultani G, Lee J, Stephan JP, Torres E, Jung K, Kuijl C, James DE, Junutula JR, Stöckli J. Trefely S, et al. Among authors: khoo ps. J Biol Chem. 2015 Oct 23;290(43):25834-46. doi: 10.1074/jbc.M115.658815. Epub 2015 Sep 4. J Biol Chem. 2015. PMID: 26342081 Free PMC article.
22 results