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Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala.
Tunstall BJ, Kirson D, Zallar LJ, McConnell SA, Vendruscolo JCM, Ho CP, Oleata CS, Khom S, Manning M, Lee MR, Leggio L, Koob GF, Roberto M, Vendruscolo LF. Tunstall BJ, et al. Among authors: khom s. PLoS Biol. 2019 Apr 16;17(4):e2006421. doi: 10.1371/journal.pbio.2006421. eCollection 2019 Apr. PLoS Biol. 2019. PMID: 30990816 Free PMC article.
Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala.
Suárez J, Khom S, Alén F, Natividad LA, Varodayan FP, Patel RR, Kirson D, Arco R, Ballesta A, Bajo M, Rubio L, Martin-Fardon R, Rodríguez de Fonseca F, Roberto M. Suárez J, et al. Among authors: khom s. Addict Biol. 2020 Sep;25(5):e12813. doi: 10.1111/adb.12813. Epub 2019 Jul 24. Addict Biol. 2020. PMID: 31339221 Free PMC article.
The Role of the Central Amygdala in Alcohol Dependence.
Roberto M, Kirson D, Khom S. Roberto M, et al. Among authors: khom s. Cold Spring Harb Perspect Med. 2021 Feb 1;11(2):a039339. doi: 10.1101/cshperspect.a039339. Cold Spring Harb Perspect Med. 2021. PMID: 31988201 Free PMC article. Review.
Microglia Control Escalation of Drinking in Alcohol-Dependent Mice: Genomic and Synaptic Drivers.
Warden AS, Wolfe SA, Khom S, Varodayan FP, Patel RR, Steinman MQ, Bajo M, Montgomery SE, Vlkolinsky R, Nadav T, Polis I, Roberts AJ, Mayfield RD, Harris RA, Roberto M. Warden AS, et al. Among authors: khom s. Biol Psychiatry. 2020 Dec 15;88(12):910-921. doi: 10.1016/j.biopsych.2020.05.011. Epub 2020 May 19. Biol Psychiatry. 2020. PMID: 32680583 Free PMC article.
37 results