Khetani SR - Search Results

1

A human iPSC-derived hepatocyte screen identifies compounds that inhibit production of Apolipoprotein B.

Liu JT, Doueiry C, Jiang YL, Blaszkiewicz J, Lamprecht MP, Heslop JA, Peterson YK, Carten JD, Traktman P, Yuan Y, Khetani SR, Twal WO, Duncan SA. Liu JT, et al. Among authors: khetani sr. Commun Biol. 2023 Apr 24;6(1):452. doi: 10.1038/s42003-023-04739-9. Commun Biol. 2023. PMID: 37095219 Free PMC article.

2

In vitro zonation and toxicity in a hepatocyte bioreactor.

Allen JW, Khetani SR, Bhatia SN. Allen JW, et al. Among authors: khetani sr. Toxicol Sci. 2005 Mar;84(1):110-9. doi: 10.1093/toxsci/kfi052. Epub 2004 Dec 8. Toxicol Sci. 2005. PMID: 15590888

3

Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication.

Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M Jr, Shah VH, Rosen HR. Giugliano S, et al. Among authors: khetani sr. Gastroenterology. 2015 Feb;148(2):392-402.e13. doi: 10.1053/j.gastro.2014.10.040. Epub 2014 Nov 4. Gastroenterology. 2015. PMID: 25447848 Free PMC article.

4

Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens.

March S, Ramanan V, Trehan K, Ng S, Galstian A, Gural N, Scull MA, Shlomai A, Mota MM, Fleming HE, Khetani SR, Rice CM, Bhatia SN. March S, et al. Among authors: khetani sr. Nat Protoc. 2015 Dec;10(12):2027-53. doi: 10.1038/nprot.2015.128. Epub 2015 Nov 19. Nat Protoc. 2015. PMID: 26584444 Free PMC article.

5

Establishment of a hepatocyte-kupffer cell coculture model for assessment of proinflammatory cytokine effects on metabolizing enzymes and drug transporters.

Nguyen TV, Ukairo O, Khetani SR, McVay M, Kanchagar C, Seghezzi W, Ayanoglu G, Irrechukwu O, Evers R. Nguyen TV, et al. Among authors: khetani sr. Drug Metab Dispos. 2015 May;43(5):774-85. doi: 10.1124/dmd.114.061317. Epub 2015 Mar 4. Drug Metab Dispos. 2015. PMID: 25739975

6

Long-term stability of primary rat hepatocytes in micropatterned cocultures.

Ukairo O, Kanchagar C, Moore A, Shi J, Gaffney J, Aoyama S, Rose K, Krzyzewski S, McGeehan J, Andersen ME, Khetani SR, Lecluyse EL. Ukairo O, et al. Among authors: khetani sr. J Biochem Mol Toxicol. 2013 Mar;27(3):204-12. doi: 10.1002/jbt.21469. Epub 2013 Jan 11. J Biochem Mol Toxicol. 2013. PMID: 23315828

7

Quantum dots to monitor RNAi delivery and improve gene silencing.

Chen AA, Derfus AM, Khetani SR, Bhatia SN. Chen AA, et al. Among authors: khetani sr. Nucleic Acids Res. 2005 Dec 13;33(22):e190. doi: 10.1093/nar/gni188. Nucleic Acids Res. 2005. PMID: 16352864 Free PMC article.

8

Microscale culture of human liver cells for drug development.

Khetani SR, Bhatia SN. Khetani SR, et al. Nat Biotechnol. 2008 Jan;26(1):120-6. doi: 10.1038/nbt1361. Epub 2007 Nov 18. Nat Biotechnol. 2008. PMID: 18026090

9

Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures.

Ploss A, Khetani SR, Jones CT, Syder AJ, Trehan K, Gaysinskaya VA, Mu K, Ritola K, Rice CM, Bhatia SN. Ploss A, et al. Among authors: khetani sr. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3141-5. doi: 10.1073/pnas.0915130107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133632 Free PMC article.

10

Hormone and Drug-Mediated Modulation of Glucose Metabolism in a Microscale Model of the Human Liver.

Davidson MD, Lehrer M, Khetani SR. Davidson MD, et al. Among authors: khetani sr. Tissue Eng Part C Methods. 2015 Jul;21(7):716-25. doi: 10.1089/ten.TEC.2014.0512. Epub 2015 Jan 30. Tissue Eng Part C Methods. 2015. PMID: 25517416 Free PMC article.

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