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Challenges and emerging directions in single-cell analysis.
Yuan GC, Cai L, Elowitz M, Enver T, Fan G, Guo G, Irizarry R, Kharchenko P, Kim J, Orkin S, Quackenbush J, Saadatpour A, Schroeder T, Shivdasani R, Tirosh I. Yuan GC, et al. Among authors: kharchenko p. Genome Biol. 2017 May 8;18(1):84. doi: 10.1186/s13059-017-1218-y. Genome Biol. 2017. PMID: 28482897 Free PMC article. Review.
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
Masuda T, Wang X, Maeda M, Canver MC, Sher F, Funnell AP, Fisher C, Suciu M, Martyn GE, Norton LJ, Zhu C, Kurita R, Nakamura Y, Xu J, Higgs DR, Crossley M, Bauer DE, Orkin SH, Kharchenko PV, Maeda T. Masuda T, et al. Among authors: kharchenko pv. Science. 2016 Jan 15;351(6270):285-9. doi: 10.1126/science.aad3312. Science. 2016. PMID: 26816381 Free PMC article.
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.
Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipilä K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT. Silberstein L, et al. Among authors: kharchenko pv. Cell Stem Cell. 2016 Oct 6;19(4):530-543. doi: 10.1016/j.stem.2016.07.004. Epub 2016 Aug 11. Cell Stem Cell. 2016. PMID: 27524439 Free PMC article.
Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia.
Wang L, Fan J, Francis JM, Georghiou G, Hergert S, Li S, Gambe R, Zhou CW, Yang C, Xiao S, Cin PD, Bowden M, Kotliar D, Shukla SA, Brown JR, Neuberg D, Alessi DR, Zhang CZ, Kharchenko PV, Livak KJ, Wu CJ. Wang L, et al. Genome Res. 2017 Aug;27(8):1300-1311. doi: 10.1101/gr.217331.116. Epub 2017 Jul 5. Genome Res. 2017. PMID: 28679620 Free PMC article.
152 results