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Vitamin C epigenetically controls osteogenesis and bone mineralization.
Thaler R, Khani F, Sturmlechner I, Dehghani SS, Denbeigh JM, Zhou X, Pichurin O, Dudakovic A, Jerez SS, Zhong J, Lee JH, Natarajan R, Kalajzic I, Jiang YH, Deyle DR, Paschalis EP, Misof BM, Ordog T, van Wijnen AJ. Thaler R, et al. Among authors: khani f. Nat Commun. 2022 Oct 6;13(1):5883. doi: 10.1038/s41467-022-32915-8. Nat Commun. 2022. PMID: 36202795 Free PMC article.
Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate.
Thaler R, Maurizi A, Roschger P, Sturmlechner I, Khani F, Spitzer S, Rumpler M, Zwerina J, Karlic H, Dudakovic A, Klaushofer K, Teti A, Rucci N, Varga F, van Wijnen AJ. Thaler R, et al. Among authors: khani f. J Biol Chem. 2016 Mar 25;291(13):6754-71. doi: 10.1074/jbc.M115.678235. Epub 2016 Jan 12. J Biol Chem. 2016. PMID: 26757819 Free PMC article.
Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing.
Dudakovic A, Gluscevic M, Paradise CR, Dudakovic H, Khani F, Thaler R, Ahmed FS, Li X, Dietz AB, Stein GS, Montecino MA, Deyle DR, Westendorf JJ, van Wijnen AJ. Dudakovic A, et al. Among authors: khani f. Gene. 2017 Apr 20;609:28-37. doi: 10.1016/j.gene.2017.01.019. Epub 2017 Jan 27. Gene. 2017. PMID: 28132772 Free PMC article.
Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice.
Dudakovic A, Camilleri ET, Paradise CR, Samsonraj RM, Gluscevic M, Paggi CA, Begun DL, Khani F, Pichurin O, Ahmed FS, Elsayed R, Elsalanty M, McGee-Lawrence ME, Karperien M, Riester SM, Thaler R, Westendorf JJ, van Wijnen AJ. Dudakovic A, et al. Among authors: khani f. J Biol Chem. 2018 Aug 17;293(33):12894-12907. doi: 10.1074/jbc.RA118.002983. Epub 2018 Jun 13. J Biol Chem. 2018. PMID: 29899112 Free PMC article.
The cancer-related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis.
Villanueva F, Araya H, Briceño P, Varela N, Stevenson A, Jerez S, Tempio F, Chnaiderman J, Perez C, Villarroel M, Concha E, Khani F, Thaler R, Salazar-Onfray F, Stein GS, van Wijnen AJ, Galindo M. Villanueva F, et al. Among authors: khani f. J Cell Physiol. 2019 Aug;234(8):13659-13679. doi: 10.1002/jcp.28046. Epub 2019 Jan 13. J Cell Physiol. 2019. PMID: 30637720
MicroRNA-101a enhances trabecular bone accrual in male mice.
Dudakovic A, Jerez S, Deosthale PJ, Denbeigh JM, Paradise CR, Gluscevic M, Zan P, Begun DL, Camilleri ET, Pichurin O, Khani F, Thaler R, Lian JB, Stein GS, Westendorf JJ, Plotkin LI, van Wijnen AJ. Dudakovic A, et al. Among authors: khani f. Sci Rep. 2022 Aug 3;12(1):13361. doi: 10.1038/s41598-022-17579-0. Sci Rep. 2022. PMID: 35922466 Free PMC article.
111 results