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Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway.
Schank M, Zhao J, Wang L, Li Z, Cao D, Nguyen LN, Dang X, Khanal S, Nguyen LNT, Thakuri BKC, Ogbu SC, Lu Z, Zhang J, Wu XY, Morrison ZD, El Gazzar M, Ning S, Moorman JP, Yao ZQ. Schank M, et al. Among authors: khanal s. Cell Death Dis. 2020 Dec 2;11(12):1030. doi: 10.1038/s41419-020-03238-7. Cell Death Dis. 2020. PMID: 33268822 Free PMC article.
Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions.
Cao D, Zhao J, Nguyan LN, Nguyen LNT, Khanal S, Dang X, Schank M, Chand Thakuri BK, Wu XY, Morrison ZD, El Gazzar M, Zou Y, Ning S, Wang L, Moorman JP, Yao ZQ. Cao D, et al. Among authors: khanal s. Front Immunol. 2019 May 22;10:1152. doi: 10.3389/fimmu.2019.01152. eCollection 2019. Front Immunol. 2019. PMID: 31191531 Free PMC article.
ATM Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy.
Zhao J, Nguyen LNT, Nguyen LN, Dang X, Cao D, Khanal S, Schank M, Thakuri BKC, Ogbu SC, Morrison ZD, Wu XY, Li Z, Zou Y, El Gazzar M, Ning S, Wang L, Moorman JP, Yao ZQ. Zhao J, et al. Among authors: khanal s. Front Immunol. 2019 Nov 5;10:2531. doi: 10.3389/fimmu.2019.02531. eCollection 2019. Front Immunol. 2019. PMID: 31781094 Free PMC article.
Inhibition of topoisomerase IIA (Top2α) induces telomeric DNA damage and T cell dysfunction during chronic viral infection.
Dang X, Ogbu SC, Zhao J, Nguyen LNT, Cao D, Nguyen LN, Khanal S, Schank M, Thakuri BKC, Wu XY, Morrison ZD, Zhang J, Li Z, El Gazzar M, Ning S, Wang L, Wang Z, Moorman JP, Yao ZQ. Dang X, et al. Among authors: khanal s. Cell Death Dis. 2020 Mar 19;11(3):196. doi: 10.1038/s41419-020-2395-2. Cell Death Dis. 2020. PMID: 32193368 Free PMC article.
Long noncoding RNA HOTAIRM1 promotes myeloid-derived suppressor cell expansion and suppressive functions through up-regulating HOXA1 expression during latent HIV infection.
Zhang J, Thakuri BKC, Zhao J, Nguyen LN, Nguyen LNT, Cao D, Dang X, Khanal S, Schank M, Lu Z, Wu XY, Morrison ZD, Gazzar ME, Li Z, Jiang Y, Ning S, Wang L, Moorman JP, Yao ZQ. Zhang J, et al. Among authors: khanal s. AIDS. 2020 Dec 1;34(15):2211-2221. doi: 10.1097/QAD.0000000000002700. AIDS. 2020. PMID: 33048872 Free PMC article.
687 results