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Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.
Campiani G, Khan T, Ulivieri C, Staiano L, Papulino C, Magnano S, Nathwani S, Ramunno A, Lucena-Agell D, Relitti N, Federico S, Pozzetti L, Carullo G, Casagni A, Brogi S, Vanni F, Galatello P, Ghanim M, McCabe N, Lamponi S, Valoti M, Ibrahim O, O'Sullivan J, Turkington R, Kelly VP, VanWemmel R, Díaz JF, Gemma S, Zisterer D, Altucci L, De Matteis A, Butini S, Benedetti R. Campiani G, et al. Among authors: khan t. Eur J Med Chem. 2022 May 5;235:114274. doi: 10.1016/j.ejmech.2022.114274. Epub 2022 Mar 20. Eur J Med Chem. 2022. PMID: 35344902
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.
Brindisi M, Ulivieri C, Alfano G, Gemma S, de Asís Balaguer F, Khan T, Grillo A, Chemi G, Menchon G, Prota AE, Olieric N, Lucena-Agell D, Barasoain I, Diaz JF, Nebbioso A, Conte M, Lopresti L, Magnano S, Amet R, Kinsella P, Zisterer DM, Ibrahim O, O'Sullivan J, Morbidelli L, Spaccapelo R, Baldari C, Butini S, Novellino E, Campiani G, Altucci L, Steinmetz MO, Brogi S. Brindisi M, et al. Among authors: khan t. Eur J Med Chem. 2019 Jan 15;162:290-320. doi: 10.1016/j.ejmech.2018.11.004. Epub 2018 Nov 3. Eur J Med Chem. 2019. PMID: 30448418
Telomerase-based Cancer Therapeutics: A Review on their Clinical Trials.
Relitti N, Saraswati AP, Federico S, Khan T, Brindisi M, Zisterer D, Brogi S, Gemma S, Butini S, Campiani G. Relitti N, et al. Among authors: khan t. Curr Top Med Chem. 2020;20(6):433-457. doi: 10.2174/1568026620666200102104930. Curr Top Med Chem. 2020. PMID: 31894749 Review.
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.
Federico S, Khan T, Fontana A, Brogi S, Benedetti R, Sarno F, Carullo G, Pezzotta A, Saraswati AP, Passaro E, Pozzetti L, Papa A, Relitti N, Gemma S, Butini S, Pistocchi A, Ramunno A, Vincenzi F, Varani K, Tatangelo V, Patrussi L, Baldari CT, Saponara S, Gorelli B, Lamponi S, Valoti M, Saccoccia F, Giannaccari M, Ruberti G, Herp D, Jung M, Altucci L, Campiani G. Federico S, et al. Among authors: khan t. Eur J Med Chem. 2022 Aug 5;238:114409. doi: 10.1016/j.ejmech.2022.114409. Epub 2022 May 1. Eur J Med Chem. 2022. PMID: 35551034
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach.
Battista T, Federico S, Brogi S, Pozzetti L, Khan T, Butini S, Ramunno A, Fiorentino E, Orsini S, Di Muccio T, Fiorillo A, Exertier C, Di Risola D, Colotti G, Gemma S, Ilari A, Campiani G. Battista T, et al. Among authors: khan t. ACS Infect Dis. 2022 Aug 12;8(8):1687-1699. doi: 10.1021/acsinfecdis.2c00325. Epub 2022 Jul 26. ACS Infect Dis. 2022. PMID: 35880849
IL-3-driven T cell-basophil crosstalk enhances antitumor immunity.
Wei J, Mayberry CL, Lv X, Hu F, Khan T, Logan NA, Wilson JJ, Sears JD, Chaussabel D, Chang CH. Wei J, et al. Among authors: khan t. Cancer Immunol Res. 2024 May 13. doi: 10.1158/2326-6066.CIR-23-0851. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38739030
Oridonin from Rabdosia rubescens: An emerging potential in cancer therapy - A comprehensive review.
Ali MA, Khan N, Ali A, Akram H, Zafar N, Imran K, Khan T, Khan K, Armaghan M, Palma-Morales M, Rodríguez-Pérez C, Caunii A, Butnariu M, Habtemariam S, Sharifi-Rad J. Ali MA, et al. Among authors: khan t. Food Sci Nutr. 2024 Feb 1;12(5):3046-3067. doi: 10.1002/fsn3.3986. eCollection 2024 May. Food Sci Nutr. 2024. PMID: 38726411 Free PMC article. Review.
2,651 results