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Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease.
Czarnota-Łydka K, Sudoł-Tałaj S, Kucwaj-Brysz K, Kurczab R, Satała G, de Candia M, Samarelli F, Altomare CD, Carocci A, Barbarossa A, Żesławska E, Głuch-Lutwin M, Mordyl B, Kubacka M, Wilczyńska-Zawal N, Jastrzębska-Więsek M, Partyka A, Khan N, Więcek M, Nitek W, Honkisz-Orzechowska E, Latacz G, Wesołowska A, Carrieri A, Handzlik J. Czarnota-Łydka K, et al. Among authors: khan n. Eur J Med Chem. 2023 Nov 5;259:115695. doi: 10.1016/j.ejmech.2023.115695. Epub 2023 Jul 30. Eur J Med Chem. 2023. PMID: 37567058 Free article.
Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and β-amyloid inhibitors for the treatment of Alzheimer's disease.
Pasieka A, Panek D, Zaręba P, Sługocka E, Gucwa N, Espargaró A, Latacz G, Khan N, Bucki A, Sabaté R, Więckowska A, Malawska B. Pasieka A, et al. Among authors: khan n. Bioorg Med Chem. 2023 Jun 6;88-89:117333. doi: 10.1016/j.bmc.2023.117333. Epub 2023 May 18. Bioorg Med Chem. 2023. PMID: 37236021 Free article.
Overcoming, and not just watching the flames.
Khan N. Khan N. Br J Gen Pract. 2024 Apr 25;74(742):195. doi: 10.3399/bjgp24X737049. Print 2024 May. Br J Gen Pract. 2024. PMID: 38664042 No abstract available.
6,294 results